Table 5 Treatment outcomes of children treated by CHWs in Iganga-Mayuge DSS

All children treated by CHWs

N = 609

N = 667

Overall treatment failure

90 (14.8%)

101 (15.1%)

0.88 (0.67-1.18)

Received additional* antibiotics

7 (1.2%)

13 (2.0%)

0.77 (0.32-1.86)

Received additional** anti-malarials

4 (0.7%)

10 (1.5%)

0.44 (0.15-1.28)

Hospitalization

10 (1.6%)

9 (1.4%)

1.47 (0.64-3.38)

Temperature ≥ 37.5°C on day 4

7 (1.2%)

23 (3.5%)

0.29 (0.11-0.78)

Had fast breathing on day 4

66 (10.8%)

48 (7.2%)

1.29 (0.87-1.92)

  Difference in fast breathing, day 1& 4†

9.2%

4.2%

p-value = 0.01

Self reported treatment failure

83 (13.7%)

170 (25.5%)

0.58 (0.46-0.74)

Children with malaria symptoms

Characteristic

Intervention

Control

RR (95% CI)

n = 589

n = 647

Overall treatment failure in malaria

84 (14.3%)

99 (15.3%)

0.85 (0.64-1.13)

Received additional* antibiotics

6 (1.0%)

13 (2.0%)

0.65 (0.26-1.65)

Received additional** anti-malarials

3 (0.5%)

10 (1.6%)

0.35 (0.11-1.11)

Hospitalization

9 (1.5%)

9 (1.4%)

1.36 (0.59-3.16)

Temperature ≥ 37.5°C on day 4

7 (1.2%)

22 (3.4%)

0.30 (0.11-0.81)

Had fast breathing on day 4

62 (10.5%)

48 (7.4%)

1.22 (0.82-1.82)

  Difference in fast breathing, day 1& 4,†

9.5%

4.0%

p-value = 0.006

Self reported treatment failure

78 (13.3%)

168 (26.0%)

0.56 (0.44-0.71)

Children with self reported pneumonia symptoms

Characteristic

Intervention

Control

RR (95% CI)

n = 251

n = 279

Overall treatment failure in “pneumonia”

43 (17.1%)

56 (20.1%)

0.77 (0.52-1.13)

Received additional* antibiotics

2 (0.8%)

10 (3.6%)

0.30 (0.08-1.21)

Received additional** anti-malarials

0 (0)

8 (2.9%)

-

Hospitalization

4 (1.6%)

3 (1.1%)

2.42 (0.60-9.84)

Temperature ≥ 37.5°C on day 4

5 (2.0%)

11 (3.9%)

0.41 (0.10-1.75)

Had fast breathing on day 4

34 (13.6%)

25 (9.0%)

1.30 (0.76-2.21)

  Difference in fast breathing, day 1& 4 †

18.3%

3.6%

p-value < 0.001

Self reported treatment failure

22 (8.8)

74 (26.5)

0.35 (0.22-0.56)