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Table 3 Comparison of MIF -794CATT STR genotype and allele frequencies among case–control groups

From: Variations in ncRNA gene LOC284889 and MIF-794CATT repeats are associated with malaria susceptibility in Indian populations

Genotype

Asymptomatic (n = 164)

Mild (n = 101)

Severe (n = 160)

Asymptomatic vs. mild malaria#

Asymptomatic vs. severe malaria#

−794 CATT

   

P-value

OR (95% CI)

P-value

OR (95% CI)

5/5

20 (12.1)

6 (5.9)

7 (4.4)

NS

---

0.015

0.33 (0.13 – 0.80)

5/6

54 (32.9)

36 (35.6)

50 (31.2)

NS

---

NS

---

6/6

72 (43.9)

48 (42.5)

78 (48.7)

NS

---

NS

---

6/7

17 (10.3)

10 (9.9)

24 (15.0)

NS

---

NS

---

7/7

1 (0.6)

1 (0.9)

1 (0.6)

NS

---

NS

---

Allele

Asymptomatic (n = 328)

Mild (n = 202)

Severe (n = 320)

P-value

OR (95% CI)

P-value

OR (95% CI)

5

94 (28.5)

48 (23.7)

64 (20.0)

NS

---

0.011

0.62 (0.43 – 0.89)

6

215 (65.5)

142 (70.2)

230 (71.9)

NS

---

NS

---

7

19 (5.79)

12 (5.9)

26 (8.1)

NS

---

NS

---

grouped

       

5

94 (28.5)

48 (23.7)

64 (20.0)

NS

 

0.01

0.62 (0.43 – 0.89)

> 5

234 (71.3)

154 (76.2)

256(80.0)

NS

---

0.01

1.61 (1.12 – 2.31)

  1. NS: Not Significant; # Fisher’s two tailed exact test; Values in parenthesis have been rounded off.