Variations in ncRNA gene LOC284889 and MIF-794CATT repeats are associated with malaria susceptibility in Indian populations

Table 4 Distribution and comparison of MIF diplotypes ( MIF -794CATT and rs34383331 T > A) in case–control groups

Haplotype	Asymptomatic (%) (Total = 328)	Mild (%) (Total = 202)	Severe (%) (Total = 320)	Asymptomatic* vs. mild malaria		Asymptomatic* vs. severe malaria
MIF-794 and rs34383331				P - value	OR (95% CI)	P - value	OR (95% CI)
6 T	202 (61.6)	122 (60.4)	194 (60.6)	NS	---	NS	---
5 T	90 (27.4)	42 (20.8)	55 (17.2)	NS	---	0.002	0.55 (0.38 – 0.80)
7A	14 (4.3)	10 (4.9)	12 (3.7)	NS	---	NS	---
6A	13 (4)	20 (9.9)	36 (11.2)	0.018	2.66 (1.29 – 5.48)	0.002	3.07 (1.59 – 5.91)
7 T	5 (1.5)	2 (1)	14 (4.4)	NS	---	NS	---
5A	4 (1.2)	6 (2.97)	9 (2.8)	NS	---	NS	---

NS Not Significant, *Fisher’s two tailed exact test; Values in parenthesis have been rounded off; P - value was corrected for multiple comparisons by Bonferroni’s method.

ISSN: 1475-2875