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Table 2 Cytoadherence of Plasmodium vivax and Plasmodium falciparum isolates in HMVEC-L basal and stimulated with TNF-α

From: Adherence to human lung microvascular endothelial cells (HMVEC-L) of Plasmodium vivax isolates from Colombia

   

Adherence (% of inhibition)

Isolate

Adherence1

Anti-CD54

P. vivax

Basal

Stimulated TNF-α

 

( code)

   

0.012

19.0 ± 1

27.0 ± 2

   ND

0.013

19.5 ± 2.5

39.5 ± 5.5

   ND

0.014

10.5 ± 1.5

33.5 ± 3.5

   ND

0.015

4.0 ± 1

24.5 ± 2.5

   ND

0.017

42.0 ± 4

51.0 ± 16

   ND

0.018

28.0 ± 3

52.0 ± 7

31.5 (39.4)

0.019

38.0 ± 9

58.5 ± 6.5

34 (41.9)

0.022

37.0 ± 11

81.5 ± 2.5

36.5 (55.2)

0.024

53.0 ± 6

77.5 ± 10.5

33.5 (56.8)

0.025

28.5 ± 6.5

67.5 ± 3.5

23.5 (56.8)

0.026

55.5 ± 7.5

69.5 ± 11.5

27 (61.2)

0.027

35.5 ± 10.5

47.0 ± 8

42 (10.6)

0.028

22.0 ± 4

48.5 ± 4.5

22 (54.6)

P. falciparum

  

0.033

58.5 ± 13.4

113 ± 16.9

 

0.034

17 ± 7.1

53 ± 8.5

 

0.035

475 ± 38.2

1050 ± 74.9

 

0.036

97 ± 8.5

259 ± 24

 

FCR3

201 ± 49.8

465 ± 61

 
  1. P. vivax and P. falciparum isolates cytoadherence to microvascular line of human lung endothelium HMVEC-L, from the isolate code 0.018 – 0.028 the percentage of adherence inhibition is described, compared to endothelial cells treated with TNF.
  2. 1. Average ± standard deviation of Pv- iEs per 200 HMVEC-L.