TY - JOUR AU - Kremsner, P. G. AU - Krishna, S. PY - 2004 DA - 2004// TI - Antimalarial combinations JO - Lancet VL - 364 UR - https://doi.org/10.1016/S0140-6736(04)16680-4 DO - 10.1016/S0140-6736(04)16680-4 ID - Kremsner2004 ER - TY - BOOK PY - 2010 DA - 2010// TI - Global report on antimalarial drug efficacy and drug resistance: 2000–2010 PB - WHO CY - Geneva ID - ref2 ER - TY - JOUR AU - Dondorp, A. M. AU - Yeung, S. AU - White, L. AU - Nguon, C. AU - Day, N. P. J. AU - Socheat, D. AU - Von Seidlein, L. PY - 2010 DA - 2010// TI - Artemisinin resistance: current status and scenarios for containment JO - Nat Rev Micro VL - 8 UR - https://doi.org/10.1038/nrmicro2385 DO - 10.1038/nrmicro2385 ID - Dondorp2010 ER - TY - JOUR AU - Jambou, R. AU - Le Bras, J. AU - Randrianarivelojosia, M. PY - 2011 DA - 2011// TI - Pitfalls in new artemisinin-containing antimalarial drug development JO - Trends Parasitol VL - 27 UR - https://doi.org/10.1016/j.pt.2010.09.004 DO - 10.1016/j.pt.2010.09.004 ID - Jambou2011 ER - TY - JOUR AU - Walsh, J. J. AU - Coughlan, D. AU - Heneghan, N. AU - Gaynor, C. AU - Bell, A. PY - 2007 DA - 2007// TI - A novel artemisinin-quinine hybrid with potent antimalarial activity JO - Bioorg Med Chem Lett VL - 17 UR - https://doi.org/10.1016/j.bmcl.2007.04.054 DO - 10.1016/j.bmcl.2007.04.054 ID - Walsh2007 ER - TY - JOUR AU - White, N. J. PY - 2004 DA - 2004// TI - Antimalarial drug resistance JO - J Clin Invest VL - 113 UR - https://doi.org/10.1172/JCI21682 DO - 10.1172/JCI21682 ID - White2004 ER - TY - JOUR AU - Ashburn, T. T. AU - Thor, K. B. PY - 2004 DA - 2004// TI - Drug repositioning: identifying and developing new uses for existing drugs JO - Nat Rev Drug Discov VL - 3 UR - https://doi.org/10.1038/nrd1468 DO - 10.1038/nrd1468 ID - Ashburn2004 ER - TY - JOUR AU - Ekins, S. AU - Williams, A. J. AU - Krasowski, M. D. AU - Freundlich, J. S. PY - 2011 DA - 2011// TI - In silico repositioning of approved drugs for rare and neglected diseases JO - Drug Discov Today VL - 16 UR - https://doi.org/10.1016/j.drudis.2011.02.016 DO - 10.1016/j.drudis.2011.02.016 ID - Ekins2011 ER - TY - JOUR AU - Walker, S. L. AU - Waters, M. F. AU - Lockwood, D. N. PY - 2007 DA - 2007// TI - The role of thalidomide in the management of erythema nodosum leprosum JO - Lepr Rev VL - 78 ID - Walker2007 ER - TY - JOUR AU - Fink, H. A. AU - Mac Donald, R. AU - Rutks, I. R. AU - Nelson, D. B. AU - Wilt, T. J. PY - 2002 DA - 2002// TI - Sildenafil for male erectile dysfunction: a systematic review and meta-analysis JO - Arch Intern Med VL - 162 UR - https://doi.org/10.1001/archinte.162.12.1349 DO - 10.1001/archinte.162.12.1349 ID - Fink2002 ER - TY - JOUR AU - DiMasa, J. A. AU - Hansen, R. W. AU - Grabowski, H. G. AU - Lasagna, L. PY - 1991 DA - 1991// TI - Cost of innovation in the pharmaceutical industry JO - J Health Econ VL - 10 UR - https://doi.org/10.1016/0167-6296(91)90001-4 DO - 10.1016/0167-6296(91)90001-4 ID - DiMasa1991 ER - TY - JOUR AU - Tartaglia, L. A. PY - 2006 DA - 2006// TI - Complementary new approaches enable repositioning of failed drug candidates JO - Expert Opin on Investig Drugs VL - 15 UR - https://doi.org/10.1517/13543784.15.11.1295 DO - 10.1517/13543784.15.11.1295 ID - Tartaglia2006 ER - TY - JOUR AU - Nzila, A. AU - Ma, Z. AU - Chibale, K. PY - 2011 DA - 2011// TI - Drug repositioning in the treatment of malaria and TB JO - Future Med Chem VL - 3 UR - https://doi.org/10.4155/fmc.11.95 DO - 10.4155/fmc.11.95 ID - Nzila2011 ER - TY - JOUR AU - Burrows, J. N. AU - Leroy, D. AU - Lotharius, J. AU - Waterson, D. PY - 2011 DA - 2011// TI - Challenges in antimalarial drug discovery JO - Future Med Chem VL - 3 UR - https://doi.org/10.4155/fmc.11.91 DO - 10.4155/fmc.11.91 ID - Burrows2011 ER - TY - JOUR AU - Lucumi, E. AU - Darling, C. AU - Jo, H. AU - Napper, A. D. AU - Chandramohandas, R. AU - Fisher, N. AU - Shone, A. E. AU - Jing, H. AU - Ward, S. A. AU - Biagini, G. A. AU - DeGrado, W. F. AU - Diamond, S. L. AU - Greenbaum, D. C. PY - 2010 DA - 2010// TI - Discovery of potent small molecule inhibitors of multi drug-resistant Plasmodium falciparum using a novel miniaturised high throughput luciferase-based assay JO - Antimicrob Agents Chemother VL - 54 ID - Lucumi2010 ER - TY - JOUR AU - Adjuik, M. AU - Agnamey, P. AU - Babiker, A. AU - Borrmann, S. AU - Brasseur, P. AU - Cisse, M. AU - Cobelens, F. AU - Diallo, S. AU - Faucher, J. F. AU - Garner, P. AU - Gikunda, S. AU - Kremsner, P. G. AU - Krishna, S. AU - Lell, B. AU - Loolpapit, M. AU - Matsiegui, P. B. AU - Missinou, M. A. AU - Mwanza, J. AU - Ntoumi, F. AU - Olliaro, P. AU - Osimbo, P. AU - Rezbach, P. AU - Some, E. AU - Taylor, W. R. PY - 2002 DA - 2002// TI - Amodiaquine-artesunate versus amodiaquine for uncomplicated Plasmodium falciparum malaria in African children: a randomised multicentre trial JO - Lancet VL - 359 UR - https://doi.org/10.1016/S0140-6736(02)08348-4 DO - 10.1016/S0140-6736(02)08348-4 ID - Adjuik2002 ER - TY - JOUR AU - Mutabingwa, T. K. AU - Anthony, D. AU - Heller, A. AU - Hallett, R. AU - Ahmed, J. AU - Drakeley, C. AU - Greenwood, B. M. AU - Whitty, C. J. PY - 2005 DA - 2005// TI - Amodiaquine alone, amodiaquine + sulfodoxine-pyremethamin, amodiaquine + artesunate and artemether-lumefantrine for outpatient treatment of malaria in Tanzanian children: a four armed randomised effectiveness trial JO - Lancet VL - 365 UR - https://doi.org/10.1016/S0140-6736(05)66417-3 DO - 10.1016/S0140-6736(05)66417-3 ID - Mutabingwa2005 ER - TY - BOOK PY - 2001 DA - 2001// TI - Antimalarial drug combination therapy (WHO/CDS/RBM/2001.35) PB - WHO CY - Geneva ID - ref18 ER - TY - CHAP AU - Read, M. AU - Hyde, J. E. PY - 1993 DA - 1993// TI - Simple in vitro culture of the malaria parasite Plasmodium falciparum (erythrocytic stages): suitable for large-scale preparations BT - Protocols in Molecular Parasitology. (Hyde JE Ed.). Volume 21 UR - https://doi.org/10.1385/0-89603-239-6:43 DO - 10.1385/0-89603-239-6:43 ID - Read1993 ER - TY - JOUR AU - Trager, W. AU - Jensen, J. B. PY - 1976 DA - 1976// TI - Human malaria parasites in continuous culture JO - Science VL - 193 UR - https://doi.org/10.1126/science.781840 DO - 10.1126/science.781840 ID - Trager1976 ER - TY - JOUR AU - Bhattacharya, A. AU - Mishra, L. C. AU - Sharma, M. AU - Awasthi, S. K. AU - Bhasin, V. K. PY - 2009 DA - 2009// TI - Antimalarial pharmacodynamics of chalcone derivatives in combination with artemisninin against Plasmodium falciparum in vitro JO - Eur J Med Chem VL - 44 UR - https://doi.org/10.1016/j.ejmech.2009.02.008 DO - 10.1016/j.ejmech.2009.02.008 ID - Bhattacharya2009 ER - TY - JOUR AU - Vossen, M. G. AU - Pferschy, S. AU - Chiba, P. AU - Noedl, H. PY - 2010 DA - 2010// TI - The SYBR Green I malaria drug sensitivity assay: performance in low parasitaemia samples JO - Am J Trop Med Hyg VL - 82 UR - https://doi.org/10.4269/ajtmh.2010.09-0417 DO - 10.4269/ajtmh.2010.09-0417 ID - Vossen2010 ER - TY - JOUR AU - Rason, M. A. AU - Randriantsoa, T. AU - Andrianantenaina, H. AU - Ratsimbasoa, A. AU - Menard, D. PY - 2008 DA - 2008// TI - Performance and reliability of the SYBR Green 1 based assay for the routine monitoring of susceptibility of Plasmodium falciparum in clinical isolates JO - Trans R Soc Trop Med Hyg VL - 102 UR - https://doi.org/10.1016/j.trstmh.2008.01.021 DO - 10.1016/j.trstmh.2008.01.021 ID - Rason2008 ER - TY - JOUR AU - Karl, S. AU - Wong, R. P. M. AU - St Pierre, T. G. AU - Davis, T. M. E. PY - 2009 DA - 2009// TI - A comparative study of a flow cytometry based assessment of in vitro Plasmodium falciparum drug sensitivity JO - Malar J VL - 8 UR - https://doi.org/10.1186/1475-2875-8-294 DO - 10.1186/1475-2875-8-294 ID - Karl2009 ER - TY - JOUR AU - Lasserre, R. PY - 1979 DA - 1979// TI - Treatment of amoebiasis JO - Phil J Microbiol Infect Dis VL - 8 ID - Lasserre1979 ER - TY - JOUR AU - Lemmens-Gruber, R. AU - Karkhaneh, A. AU - Studenik, C. AU - Heistracher, P. PY - 1996 DA - 1996// TI - Cardiotoxicity of emetine dihydrochloride by calcium channel blockade in isolated preparations and ventricular myocytes of guinea-pig hearts JO - Brit J Pharmacol VL - 117 UR - https://doi.org/10.1111/j.1476-5381.1996.tb15202.x DO - 10.1111/j.1476-5381.1996.tb15202.x ID - Lemmens-Gruber1996 ER - TY - JOUR AU - Yang, W. C. AU - Dubick, M. W. PY - 1980 DA - 1980// TI - Mechanism of Emetine toxicity JO - Pharmacol Ther VL - 10 UR - https://doi.org/10.1016/0163-7258(80)90007-8 DO - 10.1016/0163-7258(80)90007-8 ID - Yang1980 ER - TY - JOUR AU - Dempsey, J. J. AU - Salem, H. H. PY - 1966 DA - 1966// TI - An enzymatic electrocardiographic study on toxicity of dehydroemetine JO - Brit Heart J VL - 28 UR - https://doi.org/10.1136/hrt.28.4.505 DO - 10.1136/hrt.28.4.505 ID - Dempsey1966 ER - TY - JOUR AU - Chintana, T. AU - Sucharit, P. AU - Mahakittikun, V. AU - Siripanth, C. AU - Suphadtanaphongs, W. PY - 1986 DA - 1986// TI - In vitro studies on the sensitivity of local Entamoeba histolytica to anti-amoebic drugs JO - Southeast Asian J Trop Med Public Health VL - 17 ID - Chintana1986 ER - TY - JOUR AU - Bansal, D. AU - Sehgal, R. AU - Chawla, Y. AU - Mahajan, R. C. AU - Malla, N. PY - 2004 DA - 2004// TI - In vitro activity of antiamoebic drugs against clinical isolates of Entamoeba histolytica and Entamoeba dispar JO - Ann Clin Microbiol Antimicrob VL - 3 UR - https://doi.org/10.1186/1476-0711-3-27 DO - 10.1186/1476-0711-3-27 ID - Bansal2004 ER - TY - JOUR AU - Abiodun, O. O. AU - Brun, R. AU - Sergio, W. PY - 2013 DA - 2013// TI - In vitro interaction of artemisinin derivatives or the fully synthetic peroxidic antimalarial OZ277 with thapsigargin in P. falciparum strains JO - Malar J VL - 12 UR - https://doi.org/10.1186/1475-2875-12-43 DO - 10.1186/1475-2875-12-43 ID - Abiodun2013 ER - TY - JOUR AU - Vivas, L. AU - Rattray, L. AU - Stewart, L. B. AU - Robinson, B. L. AU - Fugmann, B. AU - Haynes, R. K. AU - Peters, W. AU - Croft, S. L. PY - 2007 DA - 2007// TI - Antimalarial efficacy and drug interactions of the novel semi-synthetic endoperoxide artemisone in vitro and in vivo JO - J Antimicrob Chemother VL - 59 UR - https://doi.org/10.1093/jac/dkl563 DO - 10.1093/jac/dkl563 ID - Vivas2007 ER - TY - JOUR AU - Canfield, C. J. AU - Pudney, M. AU - Gutteridge, W. E. PY - 1995 DA - 1995// TI - Interactions of atovaquone with other antimalarial drugs against Plasmodium falciparum in vitro JO - Exp Parasitol VL - 80 UR - https://doi.org/10.1006/expr.1995.1049 DO - 10.1006/expr.1995.1049 ID - Canfield1995 ER - TY - JOUR AU - Fivelman, Q. L. AU - Adagu, I. S. AU - Warhurst, D. C. PY - 2004 DA - 2004// TI - Modified fixed-ratio isbologram method for studying in vitro interactions between atovoquone and proguanil or dihydroartemisinin against drug-resistant strains of Plasmodium falciparum JO - Antimicrob Agents Chemother VL - 48 UR - https://doi.org/10.1128/AAC.48.11.4097-4102.2004 DO - 10.1128/AAC.48.11.4097-4102.2004 ID - Fivelman2004 ER - TY - CHAP AU - Bennerstrom, J. L. AU - Ellis, W. Y. AU - Milhouse, W. K. AU - Eaton, R. M. ED - Chou, T. C. ED - Rideout, D. C. PY - 2001 DA - 2001// TI - Antimalarial synergism and antagonism BT - Synergism and Antagonism in Chemotherapy PB - Academic Press, Inc CY - New York ID - Bennerstrom2001 ER - TY - JOUR AU - Bell, A. PY - 2005 DA - 2005// TI - Antimalarial synergism and antagonism: mechanistic and clinical significance JO - FEMS Microbiol Lett VL - 253 UR - https://doi.org/10.1016/j.femsle.2005.09.035 DO - 10.1016/j.femsle.2005.09.035 ID - Bell2005 ER -