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Figure 4 | Malaria Journal

Figure 4

From: Drug repositioning as a route to anti-malarial drug discovery: preliminary investigation of the in vitro anti-malarial efficacy of emetine dihydrochloride hydrate

Figure 4

Preliminary screen of five LOPAC compounds with dihydroartemisinin. The LOPAC compounds Emetine dihydrochloride hydrate (EM), SKF 95282 dimaleate (SKF), S (−)-UH-301 hydrochloride (SUH), Vinblastine (VinB) and Vincristine (VinC) were either added alone or in combination with DHA for a 48 hr treatment period. All samples were analysed using the SYBR Green flow cytometric method. Parasitized blood and parasites treated with a range of DHA concentrations served as controls. Non-infected blood was also included and background fluorescence was deducted from all samples accordingly.

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Malaria Journal

ISSN: 1475-2875

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