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Figure 5 | Malaria Journal

Figure 5

From: Ex vivo tetramer staining and cell surface phenotyping for early activation markers CD38 and HLA-DR to enumerate and characterize malaria antigen-specific CD8+ T-cells induced in human volunteers immunized with a Plasmodium falciparum adenovirus-vectored malaria vaccine expressing AMA1

Figure 5

Malaria tetramer-positive CD8+T cells also express the {CD38+HLA-DRhi} early activation phenotype. Back-gating of malaria tetramer-positive CD8+ T cells (red dots) onto the total CD8+ T cells (grey dots) shows that the former are derived primarily from the {CD38+ HLA-DRhi}-positive sub-population.

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