Table 2 Comparative indicators of Parascreen®, when using EM and qPCR as reference standard
Reference standard | Test | Results by Parascreen | ||||
|---|---|---|---|---|---|---|
Sensitivity [%(95% CI)] | Specificity [%(95% CI)] | PPV [%(95% CI)] | NPV [%(95% CI)] | Agreement (k) | ||
EM | Overall | 97.1 (93.5-98.8) | 99.1 (94.7-99.9) | 99.5 (96.8-99.9) | 95.2 (89.4-98.0) | 0.954 |
Pf | 96.0 (91.2-98.3) | 98.2 (94.6-99.5) | 98.0 (93.8-99.4) | 96.6 (92.4-98.6) | 0.945 | |
Pv | 90.7 (78.9-96.5) | 98.9 (96.5-99.7) | 94.2 (83.0-98.4) | 98.1 (95.5-99.3) | 0.910 | |
qPCR | Overall | 97.1 (93.5-98.8) | 100.0 (96.1-100.0) | 100.0 (97.6-100.0) | 95.2 (89.4-98.0) | 0.961 |
Pf | 95.4 (90.5-98.0) | 98.8 (95.4-99.7) | 98.6 (94.7-99.7) | 96.0 (94.7-99.7) | 0.945 | |
Pv | 89.0 (77.0-95.4) | 98.8 (96.5-99.7) | 94.2 (83.0-98.4) | 97.8 (95.0-99.1) | 0.899 | |