Mass drug administration for the control and elimination of Plasmodium vivax malaria: an ecological study from Jiangsu province, China

Table 2 Stratification for seasonal mass drug administration

Time period	Incidence in year prior	Target population	Daily drug regimen (adult dose)
MDA, Jiangsu Province, 1973-1976
1973-1976	n/a	All rural counties	pyrimethamine 50 mg × 2d + primaquine 30 mg × 4d
1977-1983	≥5%	Entire county	pyrimethamine 12.5 mg + primaquine 22.5 mg × 8d
	<5%	Index cases from past year with family and neighbors	pyrimethamine 12.5 mg + primaquine 22.5 mg × 8d
Focal MDA, Select counties, 2000-2009
2000-2006	≥1%	Entire village	chloroquine 400 mg × 3d + primaquine 22.5 mg × 8d
	<1%	Index cases from past 2 y with family, IFAT positive individuals from past 2 y	chloroquine 400 mg × 3d + primaquine 22.5 mg × 8d
2007	≥1%	Entire village	chloroquine 400 mg × 3d + primaquine 22.5 mg × 8d
	<1% but >1 case	Index cases from past 2 y with family and neighbors	chloroquine 400 mg × 3d + primaquine 22.5 mg × 8d
	1 case	Index cases and IFAT positive individuals from past 2 y	primaquine 22.5 mg × 8d
2008	≥3%	Entire village	chloroquine 400 mg × 3d + primaquine 22.5 mg × 8d
	1-3%	Index cases from past year with family and neighbours	chloroquine 400 mg × 3d + primaquine 22.5 mg × 8d
	<1%	Index cases from past year with family, IFAT positive individuals from past year	primaquine 22.5 mg × 8d
2009	2-3 cases	Index cases from past year with family and neighbours	chloroquine 400 mg × 3d + primaquine 22.5 mg × 8d
	1 case	Index case from past year	primaquine 22.5 mg × 8d

IFAT indirect fluorescent antibody test, IFAT surveys as a measure of past exposure were performed in select townships. In Sihong, number of IFAT positive individuals treated was 24 in 2006, 13 in 2007, and six in 2008. Village refers to a natural village, the administrative level below an administrative village.
Drug regimens are recorded as adult dosages though age adjusted doses were given to children.

ISSN: 1475-2875