Human immune responses to Plasmodium falciparum infection: molecular evidence for a suboptimal THαβ and TH17 bias over ideal and effective traditional TH1 immune response

Table 4 TH2 related gene unchanged after malaria

U	E	E/U	A	A/U	R	R/U	Gene	TH2Immune response
1.09	1.06	0.972	0.97	0.889	1.02	0.935	IL4	IL4 CD4 Tcell
1.07	1.08	1.009	0.97	0.906	1	0.934	IL4R
1.02	1.08	1.058	0.99	0.970	0.97	0.950	IL5
1.06	1	0.943	0.98	0.924	0.99	0.933	IL5R
1.08	1.1	1.018	0.95	0.879	0.92	0.851	IL9
1.08	1.08	1	0.99	0.916	0.95	0.879	IL9R
0.94	0.99	1.053	1.15	1.223	1.09	1.159	IL10
0.93	0.85	0.913	1.08	1.161	1.17	1.258	IL10RA
1.09	1.05	0.963	0.95	0.871	0.92	0.844	IL13
0.98	1.14	1.163	1.23	1.255	0.99	1.010	IL13RA1
1.13	1.01	0.893	1.01	0.893	1.01	0.893	IL13RA2
1.1	1.13	1.027	0.91	0.827	0.96	0.872	CCR3
1.08	0.96	0.888	0.98	0.907	1.01	0.935	CCR4
1.11	1.2	1.081	0.86	0.774	0.95	0.855	CCR8
1.08	1.12	1.037	0.89	0.824	0.94	0.870	CCL17
0.99	1.1	1.111	0.91	0.919	0.95	0.959	CCL22
1.09	1.04	0.954	0.92	0.844	0.93	0.853	CRTH2
1.05	0.94	0.895	1.08	1.028	0.98	0.933	CD30
0.92	0.98	1.065	1.13	1.228	1.17	1.271	OX40
1.32	1.31	0.992	0.93	0.704	0.89	0.674	OX40L
1.01	0.88	0.871	1.01	1	0.99	0.980	STAT6
1	0.92	0.92	1.18	1.18	1.16	1.16	GATA3
0.98	1	1.020	0.96	0.979	1	1.020	NFATc
0.92	0.91	0.989	1.27	1.380	1.31	1.423	Gfi-1
0.96	1.09	1.135	1.1	1.145	1.07	1.114	SPHK1
1.05	1.02	0.971	0.97	0.923	1	0.952	SH2D1A
1.12	1.08	0.964	0.87	0.776	0.85	0.758	ST2L
1.11	1.06	0.954	0.94	0.846	0.98	0.882	A3AR	Mast cell
1.1	1.13	1.027	0.91	0.827	0.96	0.872	CCR3
1.03	1.22	1.184	0.89	0.864	0.99	0.961	FCER2
1.14	0.63	0.552	1.17	1.026	1.72	1.508	FCER1A
1.09	1.13	1.036	0.93	0.853	1.01	0.926	LTC4S
0.95	0.96	1.010	1.11	1.168	1.05	1.105	MGST2
0.89	0.93	1.044	1.19	1.337	1.13	1.269	MGST3
0.92	0.92	1	0.84	0.913	0.85	0.923	CysLTR1
1.07	1.04	0.971	0.94	0.878	0.94	0.878	CysLTR2
1.02	1.08	1.058	0.99	0.970	0.97	0.950	IL5	Eosinophil
1.11	1.01	0.909	0.97	0.873	1.02	0.918	Eotaxin1
1.18	1.17	0.991	0.88	0.745	0.89	0.754	Eotaxin2

ISSN: 1475-2875