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Table 4 McC and S l alleles in various Africa populations

From: Human genetic polymorphisms in the Knops blood group are not associated with a protective advantage against Plasmodium falciparum malaria in Southern Ghana

Population

McCa/McCb

Sl1/Sl2

Ghana (n = 542)

0.73/0.27

0.17/0.83

Kenya 1 (n = 460)

0.71/0.29

0.32/0.68**

The Gambia 2 (n = 853)

0.61/0.39**

0.20/0.80

Mali 3 (n = 99)

0.69/0.31

0.24/0.76*

West Africa 3 (n = 182)

0.69/0.31

0.21/0.79

  1. Allele frequencies found in African populations for the Knops blood group alleles at the loci; McC and Sl. All studies were compared to the frequencies found in Ghana. * and ** differed significantly from the distribution seen in Ghana (p < 0.02) and (p < 0.001), respectively. 1Thathy et al.[17], 2Zimmerman et al.[24] , 3Moulds et al.[20]. The frequencies shown reflect pooled cases and controls.
  2. a and b denotes the alleles at the McCoy (McC) locus, 1 and 2 denotes the alleles at the Swain-Langley (Sl) locus.