Susceptibility of human Plasmodium knowlesi infections to anti-malarials

Malaria Journal

Table 1 Patient isolate data

Isolate	Species	% starting parasitaemia	% schizont at start of assay	Duration of *in vitro* development (h)	% schizont at end of assay
P0002	Pk	0.4	15	12	80
P0003	Pk	0.6	10	12	86
P0006	Pk	0.8	33	17	53
P0009	Pk	7.0^a	17	15	94
P0010	Pk	0.8	6	12	63
P0011	Pk	1.3	8	14	54
P0007	Pf	2.0^a	0	31	50
P0001	Pv	0.5	20	18	58
P0013	Pv	0.5	30	29	60

^aAbove Mark III assay cut-off (for examination of P. falciparum mono-infections), assuming a parasitaemia of 1.6% equates to approximately 80,000 parasites per μl of blood, and was used undiluted. Note that in both cases good schizont development was observed.
For each isolate, the species, parasitaemia and change in development over time are presented.

ISSN: 1475-2875