Figure 1
From: Evaluation of Plasmodium falciparum gametocyte detection in different patient material
Qualitative data for 18S-rRNA, the marker for asexual and sexual parasites, Pfs16-mRNA, the marker for all sexual stages, and Pfs25-mRNA, the marker for mature sexual stages (n = 15). 18S-rRNA: Sensitivity for saliva and urine were 80% and 67%, respectively. Detection in mucosa samples was the least sensitive method. Pfs16-mRNA: Detection of the target in non-invasively collected material was low. Urine performed best with a sensitivity of 20%. Pfs25-mRNA: Detection of mRNA amplicons was only achieved in blood samples. Sensitivity of the methods or size of the RNA fragments in other compartments seems to low for detection with this method.