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Table 1 Mean mefloquine concentrations, in ng/ml, in male (n = 10) and female (n = 12) healthy volunteers at 14 hours (H14), 48 hours (H48) and 168 hours (H168) after administration of the first drug dose

From: Gender-specific distribution of mefloquine in the blood following the administration of therapeutic doses

Blood

H 14

H 48

H 168

Female

Male

Female

Male

Female

Male

Whole blood

1,360

1,648

1,437

1,272

896

885

Serum

1,570

1,623

1,244

847

811

1,304

Plasma

2,778

1,017

2,106

1,214

1,353

666

RBC

719

857

633

827

389

375

WBC

35,641

33,885

32,414

29,447

17,584

16,214

Platelets

9,212

9,002

9,710

7,825

5,538

5,808