Table 2 Dihydrofolate reductase ( dhfr ) and dihydropteroate synthase ( dhps ) alleles in Plasmodium falciparum isolates from the interior division of Sabah, Malaysian Borneo

16

51

59

108

164

n = 22

A

N

R

N

L

86.4

A

I

R

N

I

4.5

A

N

R

N

I

9.1

(b)

pfdhps amino acid position

Prevalence (%)

436

437

540

581

613

n = 22

S

G

T

G

A

72.7

A

A

K

A

A

4.5

S

G

K

A

A

9.1

S

G

K

G

A

13.6