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Table 2 Summary of anti-malarial alkaloids derived from the African flora – acridones, amides and cryptolepines

From: The potential of anti-malarial compounds derived from African medicinal plants. Part I: A pharmacological evaluation of alkaloids and terpenoids

Compound subclass Isolated metabolites Plant species (Family) Part of plant studied Place of harvest (locality, country) Author, reference
Acridones 42a, b, cand 43b Teclea gerrardii a Root barka Durban, South Africaa Waffo et al.[70]a
Zanthoxylum leprieurii b Fruitsb Yaoundé, Cameroonb Tchinda et al.[71]b
Teclea trichocarpa c Leavesc   
(Rutaceae)    
44, 45, 46, 47, 48 and 49 Teclea trichocarpa (Rutaceae) Leaves Nairobi, Kenya Wurithi et al.[72]
50 Vepris uguenensis (Rutaceae) Roots Baringo District, Kenya Cheplogoi et al.[68], Kiplimo [73]
Amides 51 Hugonia castaneifolia (Linaceae) Root bark Pugu forest, Tanzania Baraza et al.[74]
52 Beilschmiedia zenkeri (Lauraceae) Bark Yaoundé, Cameroon Lenta et al.[75]
Cryptolepines 53 Sida acuta (Malvaceae) Aerial parts Ivory Coast Banzounzi et al.[76]
53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, and 63′ Cryptolepis sanguinolenta (Periplocaceae) Stemsa Mampong-Akwapim, Ghana, Guinea Bissau and other regions Barku et al.[77]a
Root barkb   Cimanga et al. [78, 79]a, b
Rootsc   Ablordeppey et al. [80]a
   Paulo et al. [81]c
   Hadden et al. [82]
  1. a,b and ccorrespond to the respective references.