TY - BOOK PY - 2012 DA - 2012// TI - World Malaria Report ID - ref1 ER - TY - BOOK AU - Dondorp, A. AU - Seidlein, L. PY - 2010 DA - 2010// TI - Infectious diseases PB - Elsevier CY - USA ID - Dondorp2010 ER - TY - JOUR AU - White, N. J. PY - 1998 DA - 1998// TI - Drug resistance in malaria JO - Brit Med Bull VL - 54 UR - https://doi.org/10.1093/oxfordjournals.bmb.a011721 DO - 10.1093/oxfordjournals.bmb.a011721 ID - White1998 ER - TY - JOUR AU - Ridley, R. G. PY - 2002 DA - 2002// TI - Medical need, scientific opportunity and the drive for antimalarial drugs JO - Nature VL - 415 UR - https://doi.org/10.1038/415686a DO - 10.1038/415686a ID - Ridley2002 ER - TY - JOUR AU - Francis, S. E. AU - Jr Sullivan, D. J. AU - Goldberg, D. E. PY - 1997 DA - 1997// TI - Hemoglobin metabolism in the malaria parasite Plasmodium falciparum JO - Annu Rev Microbiol VL - 51 UR - https://doi.org/10.1146/annurev.micro.51.1.97 DO - 10.1146/annurev.micro.51.1.97 ID - Francis1997 ER - TY - JOUR AU - Banerjee, R. AU - Liu, J. AU - Beatty, W. AU - Pelosof, L. AU - Klemba, M. AU - Goldberg, D. E. PY - 2002 DA - 2002// TI - Four plasmepsins are active in the Plasmodium falciparum food vacuole, including a protease with an active-site histidine JO - Proc Natl Acad Sci USA VL - 99 UR - https://doi.org/10.1073/pnas.022630099 DO - 10.1073/pnas.022630099 ID - Banerjee2002 ER - TY - JOUR AU - Sijwali, P. S. AU - Shenai, B. R. AU - Gut, J. AU - Singh, A. AU - Rosenthal, P. J. PY - 2001 DA - 2001// TI - Expression and characterization of the Plasmodium falciparum haemoglobinase falcipain-3 JO - Biochem J VL - 360 UR - https://doi.org/10.1042/bj3600481 DO - 10.1042/bj3600481 ID - Sijwali2001 ER - TY - JOUR AU - Rosenthal, P. J. PY - 2004 DA - 2004// TI - Cysteine proteases of malaria parasites JO - Int J Parasitol VL - 34 UR - https://doi.org/10.1016/j.ijpara.2004.10.003 DO - 10.1016/j.ijpara.2004.10.003 ID - Rosenthal2004 ER - TY - JOUR AU - Eggleson, K. K. AU - Duffin, K. L. AU - Goldberg, D. E. PY - 1999 DA - 1999// TI - Identification and characterization of falcilysin, a metallopeptidase involved in hemoglobin catabolism within the malaria parasite Plasmodium falciparum JO - J Biol Chem VL - 274 UR - https://doi.org/10.1074/jbc.274.45.32411 DO - 10.1074/jbc.274.45.32411 ID - Eggleson1999 ER - TY - JOUR AU - Klemba, M. AU - Beatty, W. AU - Gluzman, I. AU - Goldberg, D. E. PY - 2004 DA - 2004// TI - Trafficking of plasmepsin II to the food vacuole of the malaria parasite Plasmodium falciparum JO - J Cell Biol VL - 164 UR - https://doi.org/10.1083/jcb200307147 DO - 10.1083/jcb200307147 ID - Klemba2004 ER - TY - JOUR AU - Dalal, S. AU - Klemba, M. PY - 2007 DA - 2007// TI - Roles for two aminopeptidases in vacuolar hemoglobin catabolism in Plasmodium falciparum JO - J Biol Chem VL - 282 UR - https://doi.org/10.1074/jbc.M703643200 DO - 10.1074/jbc.M703643200 ID - Dalal2007 ER - TY - JOUR AU - Harbut, M. B. AU - Velmourougane, G. AU - Dalal, S. AU - Reiss, G. AU - Whisstock, J. C. AU - Onder, O. AU - Brisson, D. AU - McGowan, S. AU - Klemba, M. AU - Greenbaum, D. C. PY - 2011 DA - 2011// TI - Bestatin-based chemical biology strategy reveals distinct roles for malaria M1- and M17-family aminopeptidases JO - Proc Natl Acad Sci USA VL - 108 UR - https://doi.org/10.1073/pnas.1105601108 DO - 10.1073/pnas.1105601108 ID - Harbut2011 ER - TY - JOUR AU - Sorimachi, H. AU - Ishiura, S. AU - Suzuki, K. PY - 1997 DA - 1997// TI - Structure and physiological function of calpains JO - Biochem J VL - 328 UR - https://doi.org/10.1042/bj3280721 DO - 10.1042/bj3280721 ID - Sorimachi1997 ER - TY - JOUR AU - Drew, M. E. AU - Banerjee, R. AU - Uffman, E. W. AU - Gilbertson, S. AU - Rosenthal, P. J. AU - Goldberg, D. E. PY - 2008 DA - 2008// TI - Plasmodium food vacuole plasmepsins are activated by falcipains JO - J Biol Chem VL - 283 UR - https://doi.org/10.1074/jbc.M708949200 DO - 10.1074/jbc.M708949200 ID - Drew2008 ER - TY - JOUR AU - Kim, Y. M. AU - Lee, M. H. AU - Piao, T. G. AU - Lee, J. W. AU - Kim, J. H. AU - Lee, S. AU - Choi, K. M. AU - Jiang, J. H. AU - Kim, T. U. AU - Park, H. PY - 2006 DA - 2006// TI - Prodomain processing of recombinant plasmepsin II and IV, the aspartic proteases of Plasmodium falciparum, is auto- and trans-catalytic JO - J Biochem VL - 139 UR - https://doi.org/10.1093/jb/mvj018 DO - 10.1093/jb/mvj018 ID - Kim2006 ER - TY - JOUR AU - Shenai, B. R. AU - Sijwali, P. S. AU - Singh, A. AU - Rosenthal, P. J. PY - 2000 DA - 2000// TI - Characterization of native and recombinant falcipain-2, a principal trophozoite cysteine protease and essential hemoglobinase of Plasmodium falciparum JO - J Biol Chem VL - 275 UR - https://doi.org/10.1074/jbc.M004459200 DO - 10.1074/jbc.M004459200 ID - Shenai2000 ER - TY - JOUR AU - Coombs, G. H. AU - Goldberg, D. E. AU - Klemba, M. AU - Berry, C. AU - Kay, J. AU - Mottram, J. C. PY - 2001 DA - 2001// TI - Aspartic proteases of Plasmodium falciparum and other parasitic protozoa as drug targets JO - Trends Parasitol VL - 17 UR - https://doi.org/10.1016/S1471-4922(01)02037-2 DO - 10.1016/S1471-4922(01)02037-2 ID - Coombs2001 ER - TY - JOUR AU - Semenov, A. AU - Olson, J. E. AU - Rosenthal, P. J. PY - 1998 DA - 1998// TI - Antimalarial synergy of cysteine and aspartic protease inhibitors JO - Antimicrob Agents Ch VL - 42 ID - Semenov1998 ER - TY - JOUR AU - Moura, P. A. AU - Dame, J. B. AU - Fidock, D. A. PY - 2009 DA - 2009// TI - Role of Plasmodium falciparum digestive vacuole plasmepsins in the specificity and antimalarial mode of action of cysteine and aspartic protease inhibitors JO - Antimicrob Agents Ch VL - 53 UR - https://doi.org/10.1128/AAC.00882-09 DO - 10.1128/AAC.00882-09 ID - Moura2009 ER - TY - JOUR AU - Banerjee, R. AU - Francis, S. E. AU - Goldberg, D. E. PY - 2003 DA - 2003// TI - Food vacuole plasmepsins are processed at a conserved site by an acidic convertase activity in Plasmodium falciparum JO - Mol Biochem Parasit VL - 129 UR - https://doi.org/10.1016/S0166-6851(03)00119-1 DO - 10.1016/S0166-6851(03)00119-1 ID - Banerjee2003 ER - TY - JOUR AU - Mitchell, D. AU - Bell, A. PY - 2003 DA - 2003// TI - PEST sequences in the malaria parasite Plasmodium falciparum: a genomic study JO - Malaria J VL - 2 UR - https://doi.org/10.1186/1475-2875-2-16 DO - 10.1186/1475-2875-2-16 ID - Mitchell2003 ER - TY - JOUR AU - Wu, Y. AU - Wang, X. AU - Liu, X. AU - Wang, Y. PY - 2003 DA - 2003// TI - Data-mining approaches reveal hidden families of proteases in the genome of malaria parasite JO - Genome Res VL - 13 UR - https://doi.org/10.1101/gr.913403 DO - 10.1101/gr.913403 ID - Wu2003 ER - TY - JOUR AU - Arthur, J. S. AU - Gauthier, S. AU - Elce, J. S. PY - 1995 DA - 1995// TI - Active site residues in m-calpain: identification by site-directed mutagenesis JO - FEBS Lett VL - 368 UR - https://doi.org/10.1016/0014-5793(95)00691-2 DO - 10.1016/0014-5793(95)00691-2 ID - Arthur1995 ER - TY - JOUR AU - Russo, I. AU - Oksman, A. AU - Vaupel, B. AU - Goldberg, D. E. PY - 2009 DA - 2009// TI - A calpain unique to alveolates is essential in Plasmodium falciparum and its knockdown reveals an involvement in pre-S-phase development JO - Proc Natl Acad Sci USA VL - 106 UR - https://doi.org/10.1073/pnas.0806926106 DO - 10.1073/pnas.0806926106 ID - Russo2009 ER - TY - JOUR AU - Olaya, P. AU - Wasserman, M. PY - 1991 DA - 1991// TI - Effect of calpain inhibitors on the invasion of human erythrocytes by the parasite Plasmodium falciparum JO - Biochem Biophys Acta VL - 1096 ID - Olaya1991 ER - TY - JOUR AU - Jung, S. Y. AU - Zheng, B. AU - Choi, Y. Y. AU - Soh, B. Y. AU - Kim, S. Y. AU - Park, K. I. AU - Park, H. PY - 2009 DA - 2009// TI - Antimalarial effect of N-acetyl-L-Leucyl-L-leucyl-L-norleucinal by the inhibition of Plasmodium falciparum Calpain JO - Arch Pharm Res VL - 32 UR - https://doi.org/10.1007/s12272-009-1612-4 DO - 10.1007/s12272-009-1612-4 ID - Jung2009 ER - TY - JOUR AU - Choi, Y. Y. AU - Jung, S. Y. AU - Cho, P. Y. AU - Soh, B. Y. AU - Zheng, B. AU - Kim, S. Y. AU - Park, K. I. AU - Park, H. PY - 2010 DA - 2010// TI - Confocal microscopic findings of cysteine protease calpain in Plasmodium falciparum JO - Exp Parasitol VL - 124 UR - https://doi.org/10.1016/j.exppara.2009.10.007 DO - 10.1016/j.exppara.2009.10.007 ID - Choi2010 ER - TY - JOUR AU - Debiasi, R. L. AU - Squier, M. K. AU - Pike, B. AU - Wynes, M. AU - Dermody, T. S. AU - Cohen, J. J. AU - Tyler, K. L. PY - 1999 DA - 1999// TI - Reovirus-induced apoptosis is preceded by increased cellular calpain activity and is blocked by calpain inhibitors JO - J Virol VL - 73 ID - Debiasi1999 ER - TY - STD TI - National Center for Biotechnology Information.http://www.ncbi.nlm.nih.gov. UR - http://www.ncbi.nlm.nih.gov ID - ref29 ER - TY - STD TI - Basic Local Alignment Search Tool.http://blast.ncbi.nlm.nih.gov/Blast.cgi. UR - http://blast.ncbi.nlm.nih.gov/Blast.cgi ID - ref30 ER - TY - JOUR AU - Thompson, J. D. AU - Higgins, D. G. AU - Gibson, T. J. PY - 1994 DA - 1994// TI - CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice JO - Nucleic Acids Res VL - 22 UR - https://doi.org/10.1093/nar/22.22.4673 DO - 10.1093/nar/22.22.4673 ID - Thompson1994 ER - TY - JOUR AU - Otto, H. H. AU - Schirmeister, T. PY - 1997 DA - 1997// TI - Cysteine proteases and their inhibitors JO - Chem Rev VL - 97 UR - https://doi.org/10.1021/cr950025u DO - 10.1021/cr950025u ID - Otto1997 ER - TY - JOUR AU - Feig, M. AU - CL PY - 2004 DA - 2004// TI - Recent advances in the development and application of implicit solvent models in biomolecule simulations JO - Curr Opin Struc Biol VL - 14 UR - https://doi.org/10.1016/j.sbi.2004.03.009 DO - 10.1016/j.sbi.2004.03.009 ID - Feig2004 ER - TY - STD TI - The Structure Analysis and Verification Server.http://nihserver.mbi.ucla.edu/SAVES. UR - http://nihserver.mbi.ucla.edu/SAVES ID - ref34 ER - TY - JOUR AU - Suzuki, K. AU - Hata, S. AU - Kawabata, Y. AU - Sorimachi, H. PY - 2004 DA - 2004// TI - Structure, activation, and biology of calpain JO - Diabetes VL - 53 UR - https://doi.org/10.2337/diabetes.53.2007.S12 DO - 10.2337/diabetes.53.2007.S12 ID - Suzuki2004 ER - TY - JOUR AU - Moldoveanu, T. AU - Hosfield, C. M. AU - Lim, D. AU - Jia, Z. C. AU - Davies, P. L. PY - 2003 DA - 2003// TI - Calpain silencing by a reversible intrinsic mechanism JO - Nature Struc Biol VL - 10 UR - https://doi.org/10.1038/nsb917 DO - 10.1038/nsb917 ID - Moldoveanu2003 ER - TY - JOUR AU - Russo, I. AU - Oksman, A. AU - Goldberg, D. E. PY - 2009 DA - 2009// TI - Fatty acid acylation regulates trafficking of the unusual Plasmodium falciparum calpain to the nucleolus JO - Mol Microbiol VL - 72 UR - https://doi.org/10.1111/j.1365-2958.2009.06639.x DO - 10.1111/j.1365-2958.2009.06639.x ID - Russo2009 ER -