Methods for implementing a medicine outlet survey: lessons from the anti-malarial market

Malaria Journal

Table 1 Common adult equivalent treatment dose (AETD) reference values for anti-malarial active ingredients

Generic name	Ingredient used for AETD calculation	mg dose required for 1 AETD	Source
Quinine	Quinine	10408 (as base¹)	WHO Model Formulary, 2008
Sulphadoxine-pyrimethamine	Sulphadoxine	1500	WHO Model Formulary, 2008
Artemether-lumefantrine	Artemether	480	WHO Model Formulary, 2008
Artesunate-Amodiaquine	Artesunate	600	Manufacturer recommendations (also quoted in the WHO Guidelines for the treatment of malaria, 2^nd edition, 2010)

¹ Due to the pharmacodynamic properties of active ingredients, some medicines are manufactured as salts in order to improve the taste or slow down the absorption of the active ingredient. Care needs to be taken with such products as the strength in salt form will be greater than the base strength of the active ingredient. For example, 10,408 mg of quinine base corresponds to 12,600 mg of quinine sulphate, a common salt used in the presentation of quinine tablets.
Source: ACTwatch.

ISSN: 1475-2875