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Table 2 Comparison with microscopy and polymerase chain reaction results

From: Diagnostic performance of CareStart™ malaria HRP2/pLDH (Pf/pan) combo test versus standard microscopy on falciparum and vivax malaria between China-Myanmar endemic borders

CS RDT kit

Microscopy

PCR

Positive

Negative

Positive

Negative

Positive

113

2

115

0

Negative

13

113

13

113

Sensitivity (95% IC)%

89.68 (83.15, 93.87 )

89.84 (83.4, 93.97 )

Specificity (95% IC)%

98.26 (93.88, 99.52 )

100 (96.71, 100 )

Positive Predictive Value (95% IC)%

98.26 (93.88, 99.52 )

100 (96.77, 100 )

Negative Predictive Value (95% IC)%

89.68 (83.15, 93.87 )

89.68 (83.15, 93.87 )

Diagnostic Accuracy

93.78 (89.99, 96.19 )

94.61 (90.99, 96.82 )

Likelihood ratio of a Positive Test

51.57 (19.32 – 137.7)

-

Likelihood ratio of a Negative Test

0.11 (0.09, 0.12)

0.1 (0.09 0.12)

Diagnostic Odds

491.1 (108.3 – 2226)

-

Cohen’s kappa (Unweighted)

0.88 (0.75 – 1.00)

0.89 (0.77, 1.02)

Entropy reduction after a Positive Test%

60.44

-

Entropy reduction after a Negative Test%

36.01

35.92

Bias Index

−0.04

−0.05