Table 6 Plasmodium falciparum parasite and fever clearance times and proportion of patients with clearance on days 1, 2, and 3 (intent-to-treat population)
Outcome | PA | MQ + AS | AL |
|---|---|---|---|
Parasite clearance | Â | Â | Â |
Patients with clearance,% (n/N) | 93.7 (1923/2052) | 88.2 (373/423) | 97.5 (588/603) |
Median time to clearance, h | 24.1 | 31.9 | 24.0 |
  Africa | 23.9 | 23.9 | 24.0 |
  Asia | 32.0 | 39.2 | 31.5 |
Day 1 clearance,% (95% CI) | 48.2 (46.2, 50.2) | 33.7 (30.8, 36.8) | 51.5 (48.5, 54.6) |
Day 2 clearance,% (95% CI) | 89.9 (88.6, 91.1) | 76.1 (72.5, 79.6) | 92.0 (90.1, 93.6) |
Day 3 clearance,% (95% CI) | 94.8 (93.9, 95.6) | 84.2 (81.0, 87.1) | 96.1 (94.9, 97.2) |
Fever clearance | Â | Â | Â |
Patients with clearance,% (n/N) | 98.0 (1589/1621) | 97.8 (348/356) | 97.2 (450/463) |
Median time to clearance, h | 15.5 | 15.8 | 14.0 |
  Africa | 8.0 | 8.0 | 8.0 |
  Asia | 16.0 | 16.0 | 16.0 |
Day 1 clearance,% (95% CI) | 81.9 (80.1, 83.6) | 74.7 (70.8, 78.4) | 84.1 (81.2, 86.8) |
Day 2 clearance,% (95% CI) | 95.8 (94.9, 96.6) | 92.2 (89.8, 94.3) | 96.7 (95.4, 97.8) |
Day 3 clearance,% (95% CI) | 97.8 (97.1, 98.3) | 95.3 (93.4, 96.8) | 98.3 (97.5, 99.0) |