Skip to main content
Figure 6 | Malaria Journal

Figure 6

From: Effects of pyrethroid resistance on the cost effectiveness of a mass distribution of long-lasting insecticidal nets: a modelling study

Figure 6

Mass LLIN distribution’s effectiveness depending on insecticide susceptibility, coverage, transmission level and LLIN type. Each line represents the median number of episodes averted per person (Panels a, c, e &g) or net health benefits (NHB), which are expressed in disability adjusted life years (DALYs) averted per person (Panels b, d, f &h) of 10 simulation runs (each with unique random seed) during the mass distribution’s effective lifetime, as compared to matching non intervention scenarios, with population size 100,000. Model variant lines and red area are as in Figure 3. In the first column of panels (Panels a &b), the susceptibility to pyrethroids is varied from the most resistant population, population ‘Akron’ with estimated 1.3% mortality in 0.05% deltamethrin WHO susceptibility tests, to a less resistant population, population ‘Pitoa’ (70% mortality), to a fully susceptible population, population ‘Zeneti’ (100% mortality). The pre-intervention entomological inoculation rate (EIR) was 16 infectious bites per adult per annum (IBPAPA), and the coverage of PermaNet 3.0 (P3) LLINs was initially 70%. In the second column (Panels c &d), the initial coverage of P3 LLINs was varied between 50 and 90%. The mosquito population was ‘Pitoa’ and prior to intervention, the EIR was 16 IBPAPA. In the fourth column (Panels e &f), the pre-intervention EIR was varied between 32 and 8 IBPAPA (note the decreasing scale), with 70% initial P3 LLIN coverage and susceptibility of mosquito population ‘Pitoa’. In the fifth column (Panels g &h), P3 nets are compared to P2 at an EIR of 16 IBPAPA with 70% initial LLIN coverage and susceptibility of mosquito population ‘Pitoa’. Note that for each model variant, the middle value displayed (right hand value for the fifth column of panels) is the same for all panels in a row of panels.

Back to article page