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Table 4 Distribution of STAT6 and IL10RA haplotypes

From: Genetic evidence of regulatory gene variants of the STAT6, IL10R and FOXP3 locus as a susceptibility factor in uncomplicated malaria and parasitaemia in Congolese children

Gene ID

Haplotypes

Unc. Malaria n=358(%)

Asymptomatic n=276(%)

OR (95%CI)

P value

STAT6 (rs3024941/ rs3024943 /rs3024944)

CGG

276 (0.771)

193 (0.699)

1.4 (1.0-2.0)

0.054

GAG

43 (0.121

36 (0.130)

NA

NS

CGC

38 (0.106)

43 (0.156)

NA

NS

CAG

1 (0.002)

0 (0)

NA

NS

GAC

0 (0)

3 (0.011)

NA

NS

CAC

0 (0)

1 (0.004)

NA

NS

IL10RA (rs56356146 /rs7925112 /ss491228441)

CTT

284 (0.8)

209 (0.758)

NA

NS

TTT

44 (0.12)

40 (0.145)

NA

NS

CCT

26 (0.07)

14 (0.05)

NA

NS

CTG

3 (0.008)

13 (0.047)

0.16 (0.04-0.61)

0.007

TCT

1 (0.002)

0 (0)

NA

NS

  1. NA: not applicable; NS: not significant; Unc malar: uncomplicated malaria; Asym: asymptomatic, Odds ratio and P value were calculated by using binary logistic regression model and adjusted for age and gender.