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Table 2 dhfr / dhps and pfmdr1 haplotypes

From: Prevalence of antifolate resistance mutations in Plasmodium falciparum isolates in Afghanistan

Genes

Haplotype

Number of isolates

dhfr dhps

ANCN I

– – – – –

1

 

ANCN I

SAKAA

1

 

ANRN I

SAKAA

21

 

ANRN I

SG KAA

1

 

ANRN I

SS KG A

1

 

ANRN I

SGEG A

2

 

ANRN I

S – KAA

2

 

ANRN I

S – KG A

1

 

ANRN I

– – – – –

14

 

– – – – –

SAKAA

27

 

– – – – –

SG KG A

1

 

– – – – –

SGEG A

3

pfmdr1

NYSND

16

 

NYSN –

9

 

NYS – –

2

 

NF SND

23

 

NF SN –

21

 

NF S – –

3

 

YF SND

2

 

YF SN –

3

 

– – SND

2

 

– – SN –

4

 

– – – – –

5

  1. Haplotypes were determined by the allele at DHFR positions 16, 51, 59, 108 and 164, DHPS positions 436, 437, 540, 581 and 613 and PFMDR1 positions 86, 184, 1034, 1042 and 1246. Mutant alleles are indicated in bold.