| |
Jinja
|
Kanungu
|
Mubende
|
Apac
|
Tororo
|
|---|
|
Reported Mean MOI
|
2.62
|
2.64
|
3.01
|
4.16
|
4.46
|
|
Marker prevalence
|
0.77
|
0.62
|
0.61
|
0.89
|
0.91
|
|
(I, R, N, G and E)
|
(0.72-0.81)
|
(0.57-0.67)
|
(0.56-0.66)
|
(0.85-0.92)
|
(0.87-0.93)
|
|
Genotype frequency (IRNGE)
|
0.65
|
0.54
|
0.46
|
0.65
|
0.70
|
| |
(0.60-0.70)
|
(0.49-0.59)
|
(0.40-0.51)
|
(0.60-0.69)
|
(0.66-0.74)
|
- The reported mean MOI was extracted from the literature [31]. For each site, the prevalence of patient bloods samples that test positive for all five mutant markers (I, R, N, G, and E) in pure or mixed form was calculated by scoring mixed SNPs as mutant, then calculating the proportion of patient samples with mutant markers at each of the five SNPs (95% confidence intervals in parentheses). The frequency of the quintuple mutant genotype (IRNGE) was estimated by the model (95% credible intervals in parentheses).
