Histopathologic changes | Histopathologic grading | ||
---|---|---|---|
Normal liver | Non-hyperbilirubinaemia (TB < 51.3 μmol/L) | Hyperbilirubinaemia (TB ≥ 51.3 μmol/L) | |
Fatty change | 0 | 0 | 0 |
Kupffer cells hyperplasia | 0 | 1 | 3 |
Portal tract inflammation | 1 | 2 | 3 |
Bile duct proliferation | 0 | 0 | 0 |
Sinusoid congestion | 0 | 2 | 3 |
Haemozoin deposition | 0 | 3 | 3 |
Total histological score | 1/18 | 8/18 | 12/18 |