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Table 5 Predicted parasite clearance time by groups of parasitaemia before treatment and intervals, artesunate/amodiaquine treatment

From: Plasmodium falciparum clearance in clinical studies of artesunate-amodiaquine and comparator treatments in sub-Saharan Africa, 1999–2009

Parasitaemia at enrolment (μL) N Median   Observed     pPCT
    Day 0 Day 1 Day 2 Day 3 Day 7 hour Lower bound Upper bound
<2,500 110 2,030 100% 24% 2% 1% 0% 19.0 NA NA
2,500-5,000 227 3,680 100% 44% 7% 1% 0% 24.4 21.7 26.7
5,000-10,000 294 7,290 100% 58% 10% 1% 0% 28.2 23.8 32.5
10,000-20,000 361 14,261 100% 65% 6% 1% 0% 29.1 25.1 36.2
20,000-30,000 261 25,044 100% 68% 10% 0% 0% 30.8 25.7 35.8
30,000-50,000 362 39,250 100% 73% 9% 1% 0% 31.6 27.2 37.1
50,000-75,000 252 61,372 100% 75% 12% 2% 0% 32.9 26.8 37.5
75,000-100,000 159 86,925 100% 79% 13% 0% 0% 34.0 29.8 39.9
>100,000 329 144,357 100% 84% 18% 3% 1% 37.3 33.1 40.7
TOTAL 2,355 27,125 100% 67% 10% 1% 0% 30.8 25.8 41.8
  1. Legend: pPCT, predicted parasite clearance time.