Table 5 Predicted parasite clearance time by groups of parasitaemia before treatment and intervals, artesunate/amodiaquine treatment
Parasitaemia at enrolment (μL) | N | Median | Observed | pPCT | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
Day 0 | Day 1 | Day 2 | Day 3 | Day 7 | hour | Lower bound | Upper bound | |||
<2,500 | 110 | 2,030 | 100% | 24% | 2% | 1% | 0% | 19.0 | NA | NA |
2,500-5,000 | 227 | 3,680 | 100% | 44% | 7% | 1% | 0% | 24.4 | 21.7 | 26.7 |
5,000-10,000 | 294 | 7,290 | 100% | 58% | 10% | 1% | 0% | 28.2 | 23.8 | 32.5 |
10,000-20,000 | 361 | 14,261 | 100% | 65% | 6% | 1% | 0% | 29.1 | 25.1 | 36.2 |
20,000-30,000 | 261 | 25,044 | 100% | 68% | 10% | 0% | 0% | 30.8 | 25.7 | 35.8 |
30,000-50,000 | 362 | 39,250 | 100% | 73% | 9% | 1% | 0% | 31.6 | 27.2 | 37.1 |
50,000-75,000 | 252 | 61,372 | 100% | 75% | 12% | 2% | 0% | 32.9 | 26.8 | 37.5 |
75,000-100,000 | 159 | 86,925 | 100% | 79% | 13% | 0% | 0% | 34.0 | 29.8 | 39.9 |
>100,000 | 329 | 144,357 | 100% | 84% | 18% | 3% | 1% | 37.3 | 33.1 | 40.7 |
TOTAL | 2,355 | 27,125 | 100% | 67% | 10% | 1% | 0% | 30.8 | 25.8 | 41.8 |