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Table 1 Distribution of the pfcrt and pfmdr 1 polymorphisms of the parasites isolated from upper and lower southern areas

From: Distribution of pfmdr1 polymorphisms in Plasmodium falciparum isolated from Southern Thailand

Area

No. of isolates

pfcrt 76T

Mean pfmdr 1 copy number

pfmdr 1 mutations

86Y

184F

1034C

1042D

1246Y

Upper southern

66

66 (100%)

2.3 ± 1.0*

24 (36.4%)**

42 (63.6%)**

0 (0%)

0 (0%)

0 (0%)

Ranong

42

42 (100%)

2.6 ± 0.8

6 (14.3%)

36 (85.7%)

0 (0%)

0 (0%)

0 (0%)

Chumphon

24

24 (100%)

1.7 ± 0.9

18 (75.0%)

6 (25.0%)

0 (0%)

0 (0%)

0 (0%)

Lower southern

492

492 (100%)

1.2 ± 0.4

474 (96.3%)

16 (3.3%)

2 (0.4%)

0 (0%)

0 (0%)

Yala

215

215 (100%)

1.3 ± 0.5

204 (94.9%)

10 (4.7%)

2 (0.9%)

0 (0%)

0 (0%)

Narathiwas

234

234 (100%)

1.2 ± 0.4

228 (97.4%)

5 (2.1%)

0 (0%)

0 (0%)

0 (0%)

Songkhla

43

43 (100%)

1.2 ± 0.4

42 (97.7%)

1 (2.3%)

0 (0%)

0 (0%)

0 (0%)

  1. *Significant difference between parasites isolated from upper and lower southern area determined by Independent t test (p < 0.001).
  2. **Significant difference between parasites isolated upper and lower southern area determined by Chi square test (p < 0.001).