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Table 1 Distribution of the pfcrt and pfmdr 1 polymorphisms of the parasites isolated from upper and lower southern areas

From: Distribution of pfmdr1 polymorphisms in Plasmodium falciparum isolated from Southern Thailand

Area No. of isolates pfcrt 76T Mean pfmdr 1 copy number pfmdr 1 mutations
86Y 184F 1034C 1042D 1246Y
Upper southern 66 66 (100%) 2.3 ± 1.0* 24 (36.4%)** 42 (63.6%)** 0 (0%) 0 (0%) 0 (0%)
Ranong 42 42 (100%) 2.6 ± 0.8 6 (14.3%) 36 (85.7%) 0 (0%) 0 (0%) 0 (0%)
Chumphon 24 24 (100%) 1.7 ± 0.9 18 (75.0%) 6 (25.0%) 0 (0%) 0 (0%) 0 (0%)
Lower southern 492 492 (100%) 1.2 ± 0.4 474 (96.3%) 16 (3.3%) 2 (0.4%) 0 (0%) 0 (0%)
Yala 215 215 (100%) 1.3 ± 0.5 204 (94.9%) 10 (4.7%) 2 (0.9%) 0 (0%) 0 (0%)
Narathiwas 234 234 (100%) 1.2 ± 0.4 228 (97.4%) 5 (2.1%) 0 (0%) 0 (0%) 0 (0%)
Songkhla 43 43 (100%) 1.2 ± 0.4 42 (97.7%) 1 (2.3%) 0 (0%) 0 (0%) 0 (0%)
  1. *Significant difference between parasites isolated from upper and lower southern area determined by Independent t test (p < 0.001).
  2. **Significant difference between parasites isolated upper and lower southern area determined by Chi square test (p < 0.001).