Antibody
|
Antigen
|
Pre-acute
|
Acute
|
Convalescent
| |
---|
| |
GM1
|
GM
|
Prop. diff.2
|
95% CI
|
GM
|
Prop. diff.
|
95% CI
|
P value3
|
---|
IgG
|
MSP-119
|
0.47
|
0.73
|
1.56
|
1.20; 2.02
|
3.02
|
6.39
|
4.86; 8.40
|
< 0.0001
|
AMA-1
|
0.56
|
0.50
|
0.88
|
0.71; 1.09
|
1.01
|
1.80
|
1.44; 2.25
|
< 0.0001
|
EBA-175
|
0.53
|
0.41
|
0.77
|
0.65; 0.91
|
0.56
|
1.04
|
0.87; 1.24
|
< 0.0013
|
VSA
|
17.46
|
8.60
|
0.49
|
0.27; 0.91
|
11.58
|
0.64
|
0.39; 1.06
|
< 0.0398
|
IgM
|
MSP-119
|
0.45
|
0.68
|
1.50
|
1.29; 1.73
|
0.67
|
1.47
|
1.26; 1.72
|
< 0.0001
|
AMA-1
|
0.39
|
0.44
|
1.11
|
0.99; 1.26
|
0.48
|
1.23
|
1.08; 1.39
|
< 0.0083
|
EBA-175
|
0.42
|
0.49
|
1.14
|
1.03; 1.26
|
0.51
|
1.18
|
1.06; 1.31
|
< 0.0046
|
IgG1
|
MSP-119
|
0.30
|
0.47
|
1.54
|
1.16; 2.04
|
2.32
|
7.48
|
5.54; 10.1
|
< 0.0001
|
AMA-1
|
0.37
|
0.31
|
0.82
|
0.65; 1.04
|
0.64
|
1.73
|
1.35; 2.22
|
< 0.0001
|
EBA-175
|
0.31
|
0.21
|
0.69
|
0.59; 0.81
|
0.27
|
0.87
|
0.74; 1.03
|
< 0.0001
|
IgG3
|
MSP-119
|
0.11
|
0.15
|
1.30
|
0.99; 1.70
|
0.49
|
4.36
|
3.28; 5.78
|
< 0.0001
|
AMA-1
|
0.14
|
0.13
|
0.93
|
0.77; 1.12
|
0.29
|
2.04
|
1.66; 2.50
|
< 0.0001
|
|
EBA-175
|
0.11
|
0.07
|
0.61
|
0.52; 0.72
|
0.09
|
0.80
|
0.67; 0.95
|
< 0.0001
|
- 1Geometric means.
- 2The proportional difference is the ratio between the average levels of antibodies from acute (or convalescent) samples vs the levels from pre-acute samples, taking into account repeated measures for children.
- 3P value from Mixed-effects linear regression models using Likelihood Ratio Test.