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Table 2 Concentration of API of ATS and DHA determined with dipsticks and HPLC

From: Development of a colloidal gold-based lateral flow dipstick immunoassay for rapid qualitative and semi-quantitative analysis of artesunate and dihydroartemisinin

Ingredient

Store no.

Theoretical a.i. contenta(mg/mL)

Measured content by dipsticks (mg/mL)

Measured content by HPLCb(mg/mL)

ATS

A

2.00

1-2

1.67 ± 0.01

B

2.00

2-4

2.13 ± 0.01

DHA

A

2.00

0.8-2

1.30 ± 0.03

B

2.00

0.8-2

1.24 ± 0.01

 

C

2.00

0

0

  1. aTheoretical content of active ingredients was base on the process dissolved 50 mg of API in acetonitrile and diluted with acetonitrile to 25 mL;
  2. bData represent means of triplicates ± SD.
  3. API, active pharmaceutical ingredient; ATS, artesunate; DHA, dihydroartemisinin.