Development of a colloidal gold-based lateral flow dipstick immunoassay for rapid qualitative and semi-quantitative analysis of artesunate and dihydroartemisinin

Table 3 Concentration of ATS and DHA in commercial drugs determined with dipsticks and HPLC

Drug names	Lot no.	The claimed content (mg/pill, tube)	Theoretical a.i. content^a(mg/mL)	Measured content by dipsticks (mg/mL)	Measured content by HPLC^b(mg/mL)
ATS tablets	040502	50	2.00	2-4	2.33 ± 0.00^c
ATS tablets	AS100801	50	2.00	2-4	2.12 ± 0.01^c
ATS for injection	LA110102	60	2.00	2-4	2.12 ± 0.01^c
DHA and piperaquine phosphate tablets	030211	40	2.00	1-2.5	2.04 ± 0.03^c
	010710	40	2.00	1-2.5	2.03 ± 0.01^c
	020807	40	2.00	1-2.5	2.02 ± 0.00^c
Artesun-Plus	SH120707	100	2.00	2-4	2.21 ± 0.01
Artecospe	S130304	100	2.00	2-4	2.08 ± 0.01

^aTheoretical content of active ingredients according to the values shown on the label;
^bData represent means of triplicates ± SD.
^cData from Wang et al. 2012.

ISSN: 1475-2875