Genotype | Treatment outcomes | 95% CI |
P
|
---|
ACPR | ETF/LPF |
---|
< quintuple mutants | 6 | 8 | 1.112-2.755 | 0.024 |
≥ quintuple mutants | 0 | 10 |
Total | 6 | 18 | Â | Â |
- Quintuple mutants = the cases containing five mutations of pfdhfr 108N, 59R, 164L and pfdhps 437G, 540E or 540T, 581G.
- ACPR = adequate clinical parasitological response; ETF/LPF = parasitological failure.