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Table 1 Sensitivity, specificity, PPV and NPV of PCR of DBS, study microscopy and RDT with PCR of whole blood as a gold standard

From: PCR targeting Plasmodium mitochondrial genome of DNA extracted from dried blood on filter paper compared to whole blood

Diagnostic method

Sens (%)

Spec (%)

PPV (%)

NPV (%)

DBS PCR

41/76 (53.9)

227/227 (100.0)

41/41 (100.0)

227/262 (86.6)

Study micro

20/76 (26.3)

227/228 (99.6)

20/21 (95.2)

227/283 (80.2)

RDT

38/71 (53.5)

199/199 (100.0)

38/38 (100.0)

199/232 (85.8)

  1. PPV: positive predictive value; NPV: negative predictive value; PCR: polymerase chain reaction; DBS: dried blood spot; RDT: rapid diagnostic test for malaria; Sens: sensitivity; Spec: specificity; micro: microscopy.