Table 2 Activity anti- P. falciparum (IC 50 ) of molecules isolated from wood and/or barks of Aspidosperma sp , data described previously in the literature
From: Anti-malarial activity of indole alkaloids isolated from Aspidosperma olivaceum
Aspidosperma sp. | Molecule | IC50(μg/mL) | Reference |
|---|---|---|---|
A. desmanthum | Aspidoscarpine | 0.007 | Andrade-Neto et al.[19] |
A. marcgravianum | Aricin | 0.3 | Passemar et al.[39] |
Tchibangensin | 0.13 | ||
Tetrahydrousambarensin | 0.26 | ||
A. oblongum | Usambarensin | 0.23 | Passemar et al.[39] |
Ochrolifuanin A | 0.47 | ||
A. parvifolium | Uleine | 0.98 ± 0.20* | Oliveira et al.[17] |
A. olivaceum | Olivacine | 0.34 | Rocha e Silva et al.[35] |
A. ulei | 20-epi-dasycarpidone | 4.5 | Dos Santos Torres et al.[40] |
A. vargasii | Ellipticine | 0.2 | Rocha e Silva et al.[35] |
0.018 | Andrade-Neto et al.[19] |