TY - JOUR AU - Battle, Katherine E. AU - Karhunen, Markku S. AU - Bhatt, Samir AU - Gething, Peter W. AU - Howes, Rosalind E. AU - Golding, Nick AU - Van Boeckel, Thomas P. AU - Messina, Jane P. AU - Shanks, G. Dennis AU - Smith, David L. AU - Baird, J. Kevin AU - Hay, Simon I. PY - 2014 DA - 2014/04/15 TI - Geographical variation in Plasmodium vivax relapse JO - Malaria Journal SP - 144 VL - 13 IS - 1 AB - Plasmodium vivax has the widest geographic distribution of the human malaria parasites and nearly 2.5 billion people live at risk of infection. The control of P. vivax in individuals and populations is complicated by its ability to relapse weeks to months after initial infection. Strains of P. vivax from different geographical areas are thought to exhibit varied relapse timings. In tropical regions strains relapse quickly (three to six weeks), whereas those in temperate regions do so more slowly (six to twelve months), but no comprehensive assessment of evidence has been conducted. Here observed patterns of relapse periodicity are used to generate predictions of relapse incidence within geographic regions representative of varying parasite transmission. SN - 1475-2875 UR - https://doi.org/10.1186/1475-2875-13-144 DO - 10.1186/1475-2875-13-144 ID - Battle2014 ER -