Term | Definition |
---|---|
Infection | Presence of parasites in any of its forms of incubation, prepatency, patency, subpatency or latency. |
Incubation | The period between inoculation of sporozoites and release of merozoites into the blood stream (primary exo-erythrocytic cycle). |
Prepatency | The period prior to a primary attack where asexual parasites in the blood are both not detectable and asymptomatic, though present. |
Patency | The period of clinical attack with demonstration of asexual parasites in blood as the cause of illness. |
Subpatency | The period following a primary attack where asexual parasites are both not detectable and asymptomatic, though present. |
Recrudescence | An event following sub-patency when parasites are both demonstrated to be present and the cause of another clinical attack or asymptomatic patency. |
Latency | The period between a primary attack and a relapse; in some strains also the period between inoculation of sporozoites and the occurrence of a patent primary attack, typically six months or more. |
Relapse | Patent asexual parasitaemia originating from activation of latent hypnozoites. |
Re-infection | Patency by asexual blood stage parasites deriving from a new inoculation of sporozoites. |
Recurrence | A newly patent parasitaemia occurring at any point after clearance of sub-patency of a primary parasitaemia where the origin is not known with certainty as being a reinfection, recrudescence or relapse. |