Table 1 Clinical and laboratory parameters at baseline and follow-up on Days 3 and 7

Axillary Temperature (°C)

38.1 (37.8-38.3)

36.3 (36.2-36.5)

36.6 (36.5-36.6)

< 0.001

Respiratory rate (/min)

32 (30–32)

28 (28–28)

28 (28–28)

< 0.001

Pulse rate (/min)

124 (120–128)

108 (104–109)

104 (103.8-108)

< 0.001

Haemoglobin (g/L)

79 (75–82)

72 (70–75)

78.5 (75–81)

0.003

Total WBC (× 10⁹/L)

7.3 (6.5-7.8)

7.1 (6.6-7.4)

8.3 (7.9-8.7)

< 0.001

Leucopaenia (%)

8.3

4.8

2.4

0.015

Leucocytosis (%)

16.1

7.9

17.7

0.71

Lymphocytes (%)

34 (29–40)

50 (47–52)

45 (43–47)

< 0.001

Monocytes (%)

8 (7–9)

10 (8–11)

8 (6–9)

0.034

Granulocytes (%)

44 (38–46)

32 (30–34)

38 (35–39)

< 0.001

Platelet density (× 10⁹/L)

92 (81–107)

143.5 (130–158)

257 (240–288)

< 0.001

Thrombocytopaenia (%)

53

22.4

3

< 0.001