Simulated predictions of the comparative transmission control advantages (>one-fold) and disadvantages (<one-fold) of specific target product profiles, and combinations thereof, as a function of the baseline proportion of human exposure to vector bites occurring indoors ( π
) and the baseline proportion of blood meals obtained from humans by the vector population ( Q
). In all simulated scenarios [14–16], high demographic coverage (C
= 0.8) is assumed for personal protection products with A: toxic versus repellent properties used both indoors and outdoors; B: repellent properties that can be used indoors and outdoors versus indoors alone; and, C: repellent properties that can be used indoors and outdoors combined with an exclusively indoor-applicable toxic product versus the exclusively indoor toxic product alone. In all scenarios, all toxicity is assumed to act on contact before mosquitoes feed so that products with toxic (θ
=0) and repellent (θ
=0.8) profiles confer equivalent personal protection (ρ = 0.8) and differ only in the level of community-level protection achieved [14–16].