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Table 2 MLCR, NLCR, NMCR, and different variables stratified by immune status

From: Evidence for significant influence of host immunity on changes in differential blood count during malaria

  Semi-immune patients Non-immune patients
  Malaria negative N = 5 Malaria positive N = 66 p-value Malaria negative N = 205 Malaria positive N = 144 p-value
Female, n (%) 4 (80) 21 (32)   59 (29) 44 (31)  
Male, n (%) 1 (20) 45 (68) .030 146 (71) 100 (69) .882
Leucocytes /μL 5,900 (4,950; 7,700) 4,900 (3,900; 5,950) .096 6,000 (5,000; 7,000) 4,850 (3,925; 6,000) <.001
Monocytes in%, 5 (3; 6) 6 (3; 9) .315 6 (3; 8) 7 (4; 10) <.001
/μL 276 (162; 373) 274 (141; 436) .745 315 (196; 485) 340 (208; 503) .513
Lymphocytes in%, 36 (24; 54) 32 (22; 38) .405 34 (27; 41) 22 (14; 32) <.001
/μL 2,124 ( 1,576; 3,190) 1,325 (989; 2,041) .059 1,971 (1,563; 2,415) 1,081 (722; 1,542) <.001
Neutrophils in%, 61 (40; 67) 59 (50; 66) .857 57 (49; 65) 65 (53; 74) <.001
/μL 3,082 (2,324; 4,737) 2,880 (1,862; 3,642) .406 3,306 (2,648; 4,248) 3,006 (2,184; 4,007) .019
MLCR 0.10 (0.07; 0.21) 0.20 (0.10; 0.32) .185 0.16 (0.08; 0.22) 0.32 (0.17; 0.52) <.001
NLCR 1.69 (0.77; 2.83) 1.86 (1.31; 3.19) .574 1.70 (1.20; 2.40) 2.88 (1.66; 5.19) <.001
NMCR 11.17 (7.43; 38.75) 9.63 (6.31; 19.33) .473 10.27 (6.88; 16.81) 8.33 (5.45; 15.90) .031
Thrombocytes*1000 239 (142; 270) 116 (82; 183) .024 229 (190; 262) 117 (84; 153) <.001
/μL       
  Uncomplicated malaria, 55/66 (83) Severe malaria 11/66 (17)   Uncomplicated malaria, 117/144 (81) Severe malaria 27/144 (19)  
Female, n (%) 17 (31) 4 (36)   35 (30) 9 (33)  
Male, n (%) 38 (69) 7 (64) .723 82 (70) 18 (67) .728
Leucocytes /μL 4,900 (3,900; 5,950) 5,800 (4,600; 6,300) .068 4,700 (3,850; 5,900) 5,400 (4,000; 6,000) .249
Monocytes in%, 6 (3; 9) 3 (2; 5) .027 7 (5; 10) 7 (3; 9) .170
/μL 274 (141; 436) 210 (106; 245) .126 354 (215; 497) 280 (156; 540) .364
Lymphocytes in%, 32 (22; 38) 18 (15; 29) .004 22 (15; 32) 20 (13; 27) .213
/μL 1,325 (989; 2,041) 1,044 (828; 1,827) .049 1,113 (718; 1,534) 936 (754; 1,560) .582
Neutrophils in%, 59 (50; 66) 68 (61; 78) .006 63 (53; 75) 68 (52; 73) .732
/μL 2,880 (1,862; 3,642) 3,588 (3,339; 4,914) .005 3,000 (2,170; 3,944) 3,120 (2,250; 4,144) .519
MLCR 0.20 (0.10; 0.35) 0.25 (0.09; 0.31) .925 0.32 (0.19; 0.49) 0.31 (0.15; 0.54) .526
NLCR 1.86 (1.31; 3.19) 3.83 (2.10; 4.59) .003 2.76 (1.64; 4.84) 3.40 (2.04; 5.92) .279
NMCR 8.86 (5.78; 13.33) 23.33 (11.89; 33.38) .019 8.29 (5.36; 15.00) 9.30 (6.14; 24.08) .193
Thrombocytes (1000/μL) 116 (82; 183) 92 (59; 111) .022 124 (93; 163) 100 (51; 118) .003
  1. Medians (with 25 and 75% percentiles/IQR) of are given if not otherwise mentioned. Ranked means were compared by Mann-Wilcoxon-Whitney test and p-values were presented. P-values <0.05 are marked in bold.
  2. *times.