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Table 2 Performance characteristics of the hydrogel plastic chip compared with microscopy and conventional real-time PCR

From: A lab-on-chip for malaria diagnosis and surveillance

   Chip PCR  
   Pos (n) Neg (n) Sensitivity* (95% CI) Specificity* (95% CI) Kappa (95% CI)
Microscopy Pos (n) 137 5 96.5% (92.0 – 98.5) 63.0% (48.6 – 75.5) 0.653 (0.521 – 0.785)
Neg (n) 17 29
Conventional real-time PCR Pos (n) 152 4 97.4% (93.5 – 99.0) 93.8% (79.9 – 98.3) 0.890 (0.803 – 0.976)
Neg (n) 2 30
  1. *Determined using microscopy or conventional real-time PCR as the comparator.