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Table 2 Performance characteristics of the hydrogel plastic chip compared with microscopy and conventional real-time PCR

From: A lab-on-chip for malaria diagnosis and surveillance

  

Chip PCR

 
  

Pos (n)

Neg (n)

Sensitivity* (95% CI)

Specificity* (95% CI)

Kappa (95% CI)

Microscopy

Pos (n)

137

5

96.5% (92.0 – 98.5)

63.0% (48.6 – 75.5)

0.653 (0.521 – 0.785)

Neg (n)

17

29

Conventional real-time PCR

Pos (n)

152

4

97.4% (93.5 – 99.0)

93.8% (79.9 – 98.3)

0.890 (0.803 – 0.976)

Neg (n)

2

30

  1. *Determined using microscopy or conventional real-time PCR as the comparator.
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Malaria Journal

ISSN: 1475-2875

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