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Table 2 Ex vivo IC 50 of Plasmodium falciparum isolates against monodeshethylamodiaquine, quinine, lumefantrine, piperaquine and dihydroartemisinin by chloroquine susceptibility

From: Ex vivo anti-malarial drugs sensitivity profile of Plasmodium falciparum field isolates from Burkina Faso five years after the national policy change

Drug Chloroquine-resistant isolates (n = 161) Chloroquine-sensitive isolates (n = 221) P value
Chloroquine 289.8 [269.2 – 312.0)] 24.4 (22.8 – 26.1) 0.0001
Monodesethylamodiaquine 33.8 [31.4 – 36.4] 12.8 [12.0 – 13.6] 0.0001
Quinine 249.7 [223.3 – 279.1] 120.4 [107.2 – 135.2] 0.0001
Lumefantrine 21.9 [18.8 – 25.5] 27.8 [23.5 – 32.8] 0.0006
Piperaquine 6.5 [5.7 – 7.3] 6.1 [5.6 – 6.7] 0.382
Dihydroartemisinin 0.7 [0.6 – 0.8] 0.9 [0.8 – 1.0] 0.001