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Table 3 Sensitivity, specificity, predictive value and odds ratio of the haematological parameters in diagnosis of Malaria

From: Effect of malarial infection on haematological parameters in population near Thailand-Myanmar border

Variable Sensitivity* (95% CI) Specificity* (95% CI) PPV* (95% CI) NPV* (95% CI) OR (95% CI) PLR NLR
RBC <4×106/μL 27 (24–31) 86 (85–87) 25 (22–28) 88 (87–89) 2.4 (2–2.9) 2 0.8
Hb < 11 g/dL 35 (32–39) 68 (67–70) 15 (14–17) 87 (85–88) 1.2 (1–1.4) 1.1 0.9
MCV >100 fL 1 (0.5–2) 98 (97–99) 10 (4–19) 86 (85–87) 0.7 (0.3–1.4) 0.7 1
MCH >32 pg/cell 3 (2–5) 97 (96–97) 13 (8–19) 86 (85–87) 0.9 (0.6–1.4) 0.9 1
MCHC >37 g/dL 2 (1–4) 98 (98–99) 18 (11–28) 86 (85–87) 1.4 (0.8–2.4) 1.4 1
Platelets <150,000/μL 85 (82–87) 85 (84–86) 48 (45–51) 97 (96–98) 31.8 (25.1–39.7) 5.6 0.2
WBCs <4,000/μL 17 (14–20) 94 (93–94) 30 (26–35) 88 (87–89) 3 (2.4–3.7) 2.7 0.9
Neutrophils <2,800/μL 35 (32–39) 69 (68–70) 16 (14–17) 87 (86–89) 1.2 (1.0–1.4) 1.1 0.9
Lymphocytes <800/μL 25 (23–28) 78 (77–79) 17 (15–19) 86 (85–87) 1.4 (1.1–1.6) 1.2 1
Monocytes <80/μL 3 (2–5) 98 (97–99) 19 (12–26) 86 (85–87) 1.4 (0.9–2.2) 1.4 1
Eosinophils <40/μL 27 (24–30) 71 (69–72) 13 (11–15) 86 (84–87) 0.9 (0.8–1) 0.9 1
Basophils <16/μL 89 (86–91) 12 (11–13) 14 (13–15) 86 (83–89) 1.0 (0.8–1.3) 1 1
NL ratio >2.8 49 (45–52) 61 (60–63) 17 (15–19) 88 (87–89) 1.5 (1.3–1.8) 1 0.8
ML ratio >0.25 58 (54–62) 54 (53–56) 17 (16–19) 89 (88–90) 1.7 (1.4–1.9) 1.3 0.8
  1. PPV, positive predictive value; NPV, negative predictive value; PLR, positive likelihood ratio; NLR, negative likelihood ratio, *Percent, OR, odds ratio.