Table 1 Demographic, clinical and biochemical characteristics in children with severe malaria on day 0, day 1 and day 42

Age (months, median (± interquartile range))

36 (±26.5)

-

-

Male gender (%)

103 (57)

-

-

Temperature (°C)

37.4 (±1.2)

36.2 (±0.6)

<0.001

Parasite density (per μl)

33.804 (±15.6)

0.6 (±9.0)

<0.001

Respiratory rate (per min)

45.5 (±13.8)

31.5 (±1.2)

<0.001

pH

7.42 (±0.1)

7.42 (±0.1)

0.2

Leukocytes (per μl)

12.3 (±8.5)

9.1 (±3.8)

<0.001

Lactate (mmol/l)

5.2 (±4.2)

2.2 (±1.2)

<0.001

Glucose (mg/dl)

107.4 (±49.1)

94.2 (±18.3)

<0.001

Creatinine (mg/dl)

0.69 (±1.1)

0.36 (±0.1)

0.002