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Figure 1 | Malaria Journal

Figure 1

From: Mirincamycin, an old candidate for malaria combination treatment and prophylaxis in the 21st century: in vitro interaction profiles with potential partner drugs in continuous culture and field isolates

Figure 1

Isobolograms of mirincamycin in combination with tafenoquine, dihydroartemisinin and chloroquine. Isobolograms for the checkerboards assays of mirincamycin in combination with tafenoquine, dihydroartemisinin and chloroquine at various concentration ratios for all successfully tested isolates at FIC50 level. All individual data points (pooled FIC50s) at various concentration ratios are presented on the left hand side, isobolograms on the right side point out the geometric mean of the individual data points. The straight lines in each panel are representing the type of interaction. Data points below the 0.5-line show synergism (FIC < 0.5), around the 1.0-line are additive (FIC 0.5-2) and above the 2-line are antagonistic (FIC > 2).

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Malaria Journal

ISSN: 1475-2875

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