Study | Target population | Treatment | Alternative | Adherence overall* | Positives treated | Negatives treated |
---|---|---|---|---|---|---|
CCMm studies | ||||||
All ages, care seeking. | AL, SP <5Â kg | Complicated malaria and non-malaria febrile cases were referred to HF. | 99.9% | 99.3% | 0.2% | |
Chinkhumba[30] | >5Â years, (history of) fever | NS | Referral not mentioned. | 86.9% | 98% | 58% |
Elmardi[27] | NS | AS/SP | Complicated malaria and non-malaria febrile cases were referred to HF. | 70%** | NS | NS |
Ishengoma[28] | ≥5 years with (history of) fever | AL | Referral not specified. | 95.8% | 98.9% | 5.4% |
Mubi[24] | >3Â months, (history of) fever. Exclusion: severe disease | AL | Referral not specified. | 96.8% | 99.7% | 6.1% |
Ndiaye[20]*** | Patients of all ages, care seeking. | NS | CHW: referral of patients <2Â months, RDT negatives, severe symptoms, suspected drug adverse events. CMD: referral of all cases excluding uncomplicated malaria cases. | 88.6% | 92.0% | 20.3% |
Ndiaye[20]*** | Patients of all ages, care seeking. | NS | CHW: Referral of patients <2Â months, RDT negatives, severe symptoms, suspected drug adverse events. | 85.6% | 90.1% | 24.8% |
Ndiaye[20]*** | Patients of all ages, care seeking. | NS | CMD: Referral of all cases excluding uncomplicated malaria cases. | 93.9% | 95.3% | 10.4% |
iCCM studies | ||||||
Children 6Â months-5Â years, fever. | AL | Children with danger signs were referred to HF. | 99.3% | 98.5% | 0.4% | |
Mukanga[32] | Children <5 (history of) fever no danger signs. | AL | CHWs also diagnosed and treated pneumonia. No referral mentioned. | 97.8% | 98.6% | 4.8% |
Mukanga[34]**** | BF: 6–59 months, (history of) fever | AL | Referral for severe disease and for non-responders at day 3 after CHW visit. | 99.0% | 100% | 4.8% |
Mukanga[34]**** | Gh: 6–59 months, (history of) fever | AA | Referral for severe disease and for non-responders at day 3 after CHW visit. | 99.5% | 100% | 3.3% |
Mukanga[34]**** | Ug: 4–59 months (history of) fever. | AL | Referral for severe disease and for non-responders at day 3 after CHW visit. | 99.0% | 99.9% | 7.6% |