Study | Design | Intervention | Control | Outcome |
---|---|---|---|---|
Mubi[24] | RCT | RDT-based CCMm | Presumptive CCMm | Increased perception of recovery in control group (97.3%) versus intervention group (93.3%) at day 7. P = 0.000 |
Two malaria related deaths, one in each arm. | ||||
Thiam[25] | NRCT | RDT-based CCMm | No CCMm | Malaria related hospitalizations decreased by 43.1% in intervention areas and 40.9% in control areas. Malaria attributed deaths decreased by 62.5% in intervention areas (significant decrease) and 23.4% in control areas (no significant decrease). |
Rutta[26] | Pre-post study | RDT-based CCMm (with AL) | Comparison with pre-intervention period (presumptive CCMm with SP) | A drop of >72.0% in malaria slide positivity rate to a persistent low level of <10% was observed in the study period. |
Elmardi[27] | Pre-post study | RDT-based CCMm (with AS/SP). | Comparison with pre-intervention period (no CCMm, health centres treated with AS/SP) | 24% fever cases in last two weeks pre-intervention and 8.5% fever cases post intervention (p = 0.000). |
61 deaths (all <5 years) in the last season pre-implementation of intervention versus 1 death (>5 years) in the season post-implementation (p = 0.000). |