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Table 4 Morbidity and mortality outcomes of RDT based CCMm strategies

From: Success or failure of critical steps in community case management of malaria with rapid diagnostic tests: a systematic review

Study Design Intervention Control Outcome
Mubi[24] RCT RDT-based CCMm Presumptive CCMm Increased perception of recovery in control group (97.3%) versus intervention group (93.3%) at day 7. P = 0.000
Two malaria related deaths, one in each arm.
Thiam[25] NRCT RDT-based CCMm No CCMm Malaria related hospitalizations decreased by 43.1% in intervention areas and 40.9% in control areas. Malaria attributed deaths decreased by 62.5% in intervention areas (significant decrease) and 23.4% in control areas (no significant decrease).
Rutta[26] Pre-post study RDT-based CCMm (with AL) Comparison with pre-intervention period (presumptive CCMm with SP) A drop of >72.0% in malaria slide positivity rate to a persistent low level of <10% was observed in the study period.
Elmardi[27] Pre-post study RDT-based CCMm (with AS/SP). Comparison with pre-intervention period (no CCMm, health centres treated with AS/SP) 24% fever cases in last two weeks pre-intervention and 8.5% fever cases post intervention (p = 0.000).
61 deaths (all <5 years) in the last season pre-implementation of intervention versus 1 death (>5 years) in the season post-implementation (p = 0.000).