Table 6 Cost-effectiveness of RDT based CCMm strategies

Hawkes[21]

RDT-based CCMm for ≥5-14 years, presumptive <5 years old.

Presumptive treatment up to 14 years old.

88% by microscopy, for calculations prevalence of 80% was considered.

8.79 US$ for each case saved from unnecessary treatment (total health budget per person per year is 15$). Total costs three times as high for RDT based CCMm.

Lemma[22]

RDT-based CCMm for P. falciparum with AL, other febrile cases treated with CQ.

Two comparisons. 1. RDT-based CCMm for P. falciparum (AL) and P. vivax (CQ) and referral of all others.

Slide positivity rate 27.29%, of which 70% P. falciparum.

Intervention: 4.66 US$ per correctly treated case.

Control 1. 1.69 US$ per correctly treated case.

Control 2. 11.08 US$ per correctly treated case.

2. Presumptive treatment with AL for all fever patients.

Total costs were lowest for intervention strategy.

Chanda[23]

RDT-based CCMm with AL for all age groups (free of charge)

Health centre-based care (free of charge)

Prevalence 24% in RDT-based CCMm and 26% in health centres, either by RDT or microscopy.

Cost per case appropriately diagnosed and treated 4.22 US$ in RDT based CCMm (mainly because of higher adherence) and 6.61 US$ in health centers. Additional cost per change in case appropriately diagnosed and treated was 4.18 US$.