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Table 1 In vitro sensitivity of Plasmodium falciparum isolates (represented by IC 50 values) to chloroquine (CQ), quinine (QN), mefloquine (MQ), and artesunate (AS) and their sensitivity classification

From: Four years’ monitoring of in vitro sensitivity and candidate molecular markers of resistance of Plasmodium falciparum to artesunate-mefloquine combination in the Thai-Myanmar border

Drug Sensitivity classification % (n) IC50, nM
AS All 100 (119) 2.0 (1.7–2.3)
Sensitive (IC50 ≤2.3 nM) 58.0 (69) 1.4 (1.8–2.8)
Declined sensitivity (IC50 >2.3 nM) 42.0 (50) 3.4 (3.1–3.7)
MQ All 100 (119) 30.1 (21.8–33.3)
Sensitive 42.0 (50) 15.2 (12.8–17.6)
Resistant 58.0 (69) 54.1 (46.8–61.4)
CQ All 100 (119) 72.3 (67.3–77.3)
Sensitive 0.8 (1) 9.6
Moderate resistant 73.1 (87) 66.6 (63.5–69.7)
Highly resistant 26.1 (31) 131.6 (118.9–144.4)
QN All 100 (119) 231.7 (192.2–271.2)
Sensitive 86.6 (103) 222.6 (195.5–249.8)
Resistant 13.4 (16) 648.9 (621.2–676.5)
  1. Data presented as median (95% CI) and percentage (number).