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Figure 10 | Malaria Journal

Figure 10

From: Ultrastructure of the lung in a murine model of malaria-associated acute lung injury/acute respiratory distress syndrome

Figure 10

Diagram showing main findings of the paper. Using scanning electron microscopy a number of differences are visible in ALI/ARDS mouse lungs when compared to lungs of non-infected mice. In summary the endothelium of the capillaries ALI/ARDS lungs are swollen with distended cytoplasmic extensions and thickened basement membranes. The capillaries themselves are completely congested with leukocytes, niRBC and iRBC, in some instances bridges between iRBC and endothelium surfaces are visible. The alveolar space contains oedema, inflammatory cells and projections from septum epithelium, the septum are thick and full of leukocytes. ALI/ARDS: acute lung injury/acute respiratory distress syndrome. The layout of a single alveoli split to compare non-diseased and diseased lungs is based on a number of previous papers and books [25, 16, 26, 27].

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