Lungs from non-infected mice and mice suffering ALI/ARDS. General morphology of non-infected control lungs (A and B) compared to ALI/ARDS lungs (C and D). Seen by light (A and C) and transmission electron (B and D) microscopy. (D) ALI/ARDS lung shows oedema, haemorrhages and thickened septa filled with congested capillaries, infected red blood cell, and leukocytes (iRBC). ALI/ARDS lung, lung from DBA/2 mouse that died with acute lung injury/acute respiratory distress syndrome after infection with P. berghei ANKA; AS, alveolar space; C, capillary; L, leukocyte.