Table 7 Association of placental falciparum histologically-confirmed infection and birth weight, gestational age and maternal haemoglobin – multivariate analysis
| Â | Adjusted birth weight | Adjusted gestational age | Adjusted maternal haemoglobin | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Factors | N | Mean (SD) | Mean difference (95% CI) | p | Mean GA (SD) | Mean difference (95% CI) | p | N | Mean Hb (SD) | Mean difference (95% CI) | p |
1. Infection based on histopathology[3] | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Acute | 16 | 2232 (541) | -400 (-687, -113) | 0.001 | 36.5 (1.3) | -0.8 (-1.6,-0.04) | 0.06 | 20 | 8.8 (2.4) | -1.4 (-2.4,-0.5) | 0.02 |
Chronic | 17 | 2594 (481) | -38 (-316, 240) | Â | 37.0 (1.2) | -0.3 (-1.2, 0.45) | Â | 18 | 10.6 (2.2) | 0.1(-0.8, 1.1) | Â |
Past | 12 | 2820 (518) | 188 (-141, 517) | Â | 37.3 (1.1) | 0.0 (-0.9, 1.0) | Â | 11 | 10.4 (2.1) | -0.1(-1.5,1.0) | Â |
No infection | 419 | 2632 (442) | Reference | Â | 37.3 (1.3) | Reference | Â | 442 | 10.5 (2.1) | Reference | Â |
2. Placental infection based on | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Para + p monoc | 16 | 2274 (516) | -356 (-580, -132) | 0.01 | 36.6 (1.2) | -0.6 (-1.3, 0.02) | 0.04 | 19 | 9.3 (2.7) | -1.1 (-2.1, -0.1) | 0.016 |
Parasites only | 17 | 2588 (523) | -42 (-257, 173) | Â | 36.7 (1.3) | -0.5 (-1.2, 0.07) | Â | 19 | 10.2 (2.1) | -0.2 (-1.2, 0.8) | Â |
No infection | 431 | 2630 (444) | Reference | Â | 37.3 (1.3) | Reference | Â | 453 | 10.4 (2.2) | Reference | Â |
3. Placental infection based on | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Para + ms p monoc | 3 | 2031 (582) | -600 (-1108,-92) | 0.01 | 36.2 (1.0) | -1.1 (-2.6, 0.3) | 0.05 | 4 | 9.1 (1.5) | -1.4 (-3.4, 0.8) | 0.041 |
Para + mi p monoc | 13 | 2329 (507) | -302 (-547, -56) | Â | 36.7 (1.2) | -0.6 (-1.2, 0.2) | Â | 15 | 9.2 (2.9) | -1.3 (-2.2, 0.1) | Â |
Parasites only | 17 | 2588 (523) | - 43 (-258,173) | Â | 36.7 (1.4) | -0.6 (-1.2, 0.1) | Â | 19 | 10.2 (2.2) | -0.3 (-1.2, 0.7) | Â |
No infection | 431 | 2631 (444) | Reference | Â | 37.3 (1.3) | Reference | Â | 453 | 10.5 (2.2) | Reference | Â |
4. Sub-patent infections* | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Para + p monoc | 3 | 2446 (490) | -177 (-616, 263) | 0.4 | 37.0 (0.8) | -0.3 (-1.6, 0.9) | 0.8 | 4 | 10.4 (4.1) | -0.1 (-2.1, 2.1) | 0.9 |
Parasites only | 8 | 2778 (430) | 155 (-151, 461) | Â | 37.2 (1.4) | -0.1 (-1.0, 0.8) | Â | 8 | 10.7 (1.5) | -0.2 (-1.1, 1.6) | Â |
No infection | 431 | 2623 (444) | Reference | Â | 37.3 (1.3) | Reference | Â | 453 | 10.5 (2.1) | Reference | Â |